Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice [PDF]
Background: Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation, complicates cross-study comparisons and a global ...
Brinkman, Brigitta +7 more
core +3 more sources
Microbial diversity in individuals and their household contacts following typical antibiotic courses. [PDF]
BackgroundAntibiotics are a mainstay of treatment for bacterial infections worldwide, yet the effects of typical antibiotic prescriptions on human indigenous microbiota have not been thoroughly evaluated.
Abeles, Shira R +7 more
core +2 more sources
Nitric oxide production by the human intestinal microbiota by dissimilatory nitrate reduction to ammonium [PDF]
The free radical nitric oxide (NO) is an important signaling molecule in the gastrointestinal tract. Besides eukaryotic cells, gut microorganisms are also capable of producing NO. However, the exact mechanism of NO production by the gut microorganisms is
Vermeiren, Joan +4 more
core +2 more sources
Interactions between dietary chicory, gut microbiota and immune responses [PDF]
This thesis provides a better understanding of interactions between diet, gut microbiota, and immune responses to a specific dietary fiber source, chicory (Cichorium intybus L).
Liu, Haoyu
core
Geographical location influences the composition of the gut microbiota in wild house mice (Mus musculus domesticus) at a fine spatial scale. [PDF]
The composition of the mammalian gut microbiota can be influenced by a multitude of environmental variables such as diet and infections. Studies investigating the effect of these variables on gut microbiota composition often sample across multiple ...
Birtles, RJ +9 more
core +4 more sources
Kynurenine pathway metabolism and the microbiota-gut-brain axis [PDF]
It has become increasingly clear that the gut microbiota influences not only gastrointestinal physiology but also central nervous system (CNS) function by modulating signalling pathways of the microbiota-gut-brain axis.
Clarke, Gerard +3 more
core +1 more source
Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration. [PDF]
Background & aimsAll-trans Retinoic acid (RA) regulates hepatic lipid and bile acid homeostasis. Similar to bile acid (BA), RA accelerates partial hepatectomy (PHx)-induced liver regeneration.
Hu, Ying +2 more
core +2 more sources
明确脑小血管病(cerebral small vessel disease,CSVD)的代谢危险因素并进行及时、系统的管控至关重要。目前残余代谢危险因素与CSVD的相关性尚存争议,而靶向危险因素治疗CSVD的临床效果尚缺乏循证依据。本文综合分析炎症、肠道菌群紊乱、高同型半胱氨酸血症及高尿酸血症等残余代谢危险因素与CSVD发生、发展的相关性,进一步探讨靶向代谢危险因素的潜在治疗方案,强调代谢组学在CSVD新型代谢生物标志物发现和风险预测模型建立中的重要作用,并展望未来研究方向,为CSVD的早期诊断 ...
邱悦1,2,徐阳2,薛婧2,3,4,许杰2,3,4,王伊龙3,4 (QIU Yue1,2, XU Yang2, XUE Jing2,3,4, XU Jie2,3,4, WANG Yilong3,4 )
doaj +1 more source
Prebiotic effects of wheat Arabinoxylan related to the increase in Bifidobacteria, Roseburia and bacteroides/Prevotella in diet-induced obese mice [PDF]
Background: Alterations in the composition of gut microbiota - known as dysbiosis - has been proposed to contribute to the development of obesity, thereby supporting the potential interest of nutrients targeting the gut with beneficial effect for host ...
Neyrinck, Audrey M +7 more
core +2 more sources
The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]
Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
core +1 more source

