The impact of sequence database choice on metaproteomic results in gut microbiota studies [PDF]
Background: Elucidating the role of gut microbiota in physiological and pathological processes has recently emerged as a key research aim in life sciences.
Addis, Maria Filippa +10 more
core +4 more sources
Gut-Derived Serum Lipopolysaccharide is Associated With Enhanced Risk of Major Adverse Cardiovascular Events in Atrial Fibrillation: Effect of Adherence to Mediterranean Diet [PDF]
Gut microbiota is emerging as a novel risk factor for atherothrombosis, but the predictive role of gut-derived lipopolysaccharide (LPS) is unknown. We analyzed (1) the association between LPS and major adverse cardiovascular events (MACE) in atrial ...
Cammisotto, Vittoria +8 more
core +1 more source
Lymphoma caused by intestinal microbiota. [PDF]
The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions ...
Schiestl, Robert H, Yamamoto, Mitsuko L
core +2 more sources
Isotopic and genetic methods reveal the role of the gut microbiome in mammalian host essential amino acid metabolism. [PDF]
Intestinal microbiota perform many functions for their host, but among the most important is their role in metabolism, especially the conversion of recalcitrant biomass that the host is unable to digest into bioavailable compounds.
Bradley, Christina J +5 more
core +1 more source
Gut microbiota and brain function: an evolving field in neuroscience [PDF]
There is a growing appreciation of the importance of gut microbiota to health and disease. This has been driven by advances in sequencing technology and recent findings demonstrating the important role of microbiota in common health disorders such as ...
Cryan, John F. +3 more
core +1 more source
目的 通过建立急性轻型缺血性卒中(mild ischemic stroke,MIS)患者队列,探索肠道微生物群与MIS患者临床功能预后间的关系,寻找不良功能预后的干预靶点。 方法 前瞻性连续纳入2018年9月—2023年3月于南方医科大学南方医院神经内科住院的卒中事件后7 d内入院的急性MIS(入院NIHSS评分≤5分)患者,根据90 d随访评估结果,分为预后良好(mRS评分≤2分)组及预后不良(mRS评分>2分)组。入院后24 h内收集入组患者粪便样本 ...
任悦冉,梁京儒,郑逸锋,尹恝 (REN Yueran, LIANG Jingru, ZHENG Yifeng, YIN Jia )
doaj +1 more source
针灸作为传统医学的重要组成部分,近年来在缺血性卒中治疗中的机制受到广泛关注。本文对针灸通过干预脑-肠轴治疗缺血性卒中的相关基础研究进行汇总分析,发现其可能涉及以下机制:其一,调节肠道菌群组成,抑制致病菌增殖并促进有益菌定植,同时增强肠上皮紧密连接蛋白表达以维持肠道屏障功能,减少肠源性毒素入血;其二,通过神经内分泌调控抑制下丘脑-垂体-肾上腺轴过度激活,降低促炎因子释放,并激活迷走神经介导的抗炎通路;其三,调节短链脂肪酸、氧化三甲胺等肠道菌群代谢产物的动态平衡,改善全身炎症微环境;其四 ...
赵乾坤1,2,李宪东2,徐天策2,陈会生1,2 (ZHAO Qiankun1,2, LI Xiandong2, XU Tiance2, CHEN Huisheng1,2 )
doaj +1 more source
Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential [PDF]
The spread of multidrug resistance among pathogenic organisms threatens the efficacy of antimicrobial treatment options. The human gut serves as a reservoir for many drug-resistant organisms and their resistance genes, and perturbation of the gut ...
Bulow, Christopher +13 more
core +2 more sources
Research progress on the regulation of intestinal microbiota by milk polar lipids(乳极性脂调控肠道微生物的研究进展)
Milk polar lipids (MPLs), which include mainly glycerophosphatides (phosphatidylcholine, phosphatidyl-ethanolamine, etc.) and sphingomyelin, are important bioactive components in breast milk and dairy products.
CAI Nianbin(蔡年彬) +3 more
doaj +1 more source
Exposure to cadmium (Cd) can damage the bone microstructure and cause osteoporosis, but there is currently a lack of effective intervention strategies. In this study, a rat model of Cd exposure (drinking 50 mg/L CdCl2 aqueous solution for 8 weeks) and an
GAO Xiaojiao(高小娇) +5 more
doaj +1 more source

