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Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy

MedComm
Dysbiosis refers to the disruption of the gut microbiota balance and is the pathological basis of various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, and ...
Yao Shen, Nairui Fan, Shu‐xia Ma, Xin Cheng, Xuesong Yang, Guang Wang   +5 more
doaj   +4 more sources

Maternal Gut Dysbiosis Alters Offspring Microbiota and Social Interactions

Microorganisms, 2021
Increasing application of antibiotics changes the gut microbiota composition, leading to dysbiosis of the gut microbiota. Although growing evidence suggests the potential role of gut dysbiosis as the cause of neurodevelopmental disorders and behavioral ...
Zihan Zhang, Chao Xue, Mengyao Ju, Jiawei Guo, Minghui Wang, Sijie Yi, Xianfeng Yi   +6 more
doaj   +2 more sources

Studies of xenobiotic-induced gut microbiota dysbiosis: from correlation to mechanisms

Gut Microbes, 2021
Environmental chemicals can alter gut microbial community composition, known as dysbiosis. However, the gut microbiota is a highly dynamic system and its functions are still largely underexplored.
Liang Chi, Pengcheng Tu, Hongyu Ru, Kun Lu   +3 more
doaj   +2 more sources

Regulatory effects of marine polysaccharides on gut microbiota dysbiosis: A review

Food Chemistry: X, 2022
The gut microbiota dysbiosis is a state which the physiological combinations of flora are transformed into pathological combinations caused by factors such as diets, pollution, and drugs.
Jieying Ou, Zhuo Wang, Xiaofei Liu, Bingbing Song, Jianping Chen, Rui Li, Xuejing Jia, Riming Huang, Wenzhou Xiang, Saiyi Zhong   +9 more
doaj   +3 more sources

Chronic Antibiotic Use, Gut Microbiota Dysbiosis, and Increased Risk of Colorectal Cancer: An Emerging Threat [PDF]

Health Science Reports
Background and Aims The gut microbiota plays a vital role in host health by regulating metabolic processes, immune function, and epithelial barrier functions.
Md Mohiuddin
doaj   +2 more sources

Analysis of the Relationship Between the Degree of Dysbiosis in Gut Microbiota and Prognosis at Different Stages of Primary Hepatocellular Carcinoma

Frontiers in Microbiology, 2019
Gut microbiota dysbiosis is closely associated with primary hepatocellular carcinoma (HCC). Recent studies have evaluated the early diagnosis of primary HCC through analysis of gut microbiota dysbiosis.
Jiajia Ni, Jiajia Ni, Rong Huang, Huifang Zhou, Xiaoping Xu, Xiaoping Xu, Yang Li, Yang Li, Peihua Cao, Peihua Cao, Kebo Zhong, Kebo Zhong, Mei Ge, Mei Ge, Xiaoxia Chen, Xiaoxia Chen, Baohua Hou, Min Yu, Baogang Peng, Qiao Li, Peng Zhang, Yi Gao, Yi Gao   +22 more
doaj   +3 more sources

Gut Microbiota Dysbiosis Aggravates Mycoplasma gallisepticum Colonization in the Chicken Lung

Frontiers in Veterinary Science, 2021
Mycoplasma gallisepticum (MG) is the pathogen that causes chronic respiratory diseases in chickens. Gut microbiota plays an important role in maintaining body health and resisting respiratory infection, but the correlation between gut microbiota and MG ...
Jian Wang, Xueping Chen, Jichang Li, Muhammad Ishfaq   +3 more
doaj   +1 more source

Gut Microbial Dysbiosis Associated with Type 2 Diabetes Aggravates Acute Ischemic Stroke

mSystems, 2021
Type 2 diabetes (T2D) is an independent risk factor for acute ischemic stroke (AIS), but the underlying mechanisms remain elusive. Because the gut microbiota plays a causal role in both T2D and AIS, we wondered whether gut dysbiosis in T2D aggravates ...
Xiaojiao Chen, Qiheng Wu, Xuxuan Gao, Huidi Wang, Jiajia Zhu, Genghong Xia, Yan He, Wei Song, Kaiyu Xu   +8 more
doaj   +1 more source

Thioredoxin/Glutaredoxin Systems and Gut Microbiota in NAFLD: Interplay, Mechanism, and Therapeutical Potential

Antioxidants, 2023
Non-alcoholic fatty liver disease (NAFLD) is a common clinical disease, and its pathogenesis is closely linked to oxidative stress and gut microbiota dysbiosis.
Minghui Zhu, Omer M. A. Dagah, Billton Bryson Silaa, Jun Lu   +3 more
doaj   +1 more source

Dysbiosis: The first hit for digestive system cancer

Frontiers in Physiology, 2022
Gastrointestinal cancer may be associated with dysbiosis, which is characterized by an alteration of the gut microbiota. Understanding the role of gut microbiota in the development of gastrointestinal cancer is useful for cancer prevention and gut ...
Si Mei, Si Mei, Zhe Deng, Zhe Deng, Yating Chen, Yating Chen, Dimin Ning, Dimin Ning, Yinmei Guo, Xingxing Fan, Ruoyu Wang, Ruoyu Wang, Yuelin Meng, Yuelin Meng, Qing Zhou, Xuefei Tian, Xuefei Tian   +16 more
doaj   +1 more source