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Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy
MedCommDysbiosis refers to the disruption of the gut microbiota balance and is the pathological basis of various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, and ...
Yao Shen +5 more
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Gut microbiota dysbiosis precedes NEC [PDF]
Nature Reviews Gastroenterology & Hepatology, 2016 Hugh Thomas
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Gut Microbiota Dysbiosis in Functional Dyspepsia [PDF]
Microorganisms, 2020 Functional dyspepsia (FD) is one of the most prevalent chronic functional gastrointestinal disorders. Several distinct pathophysiological mechanisms, including gastro duodenal motor disorders, visceral hypersensitivity, brain-gut interactions, duodenal subtle inflammation, and genetic susceptibility, have been implicated in the pathogenesis of the ...
Georgios Tziatzios +6 more
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Periodontitis may induce gut microbiota dysbiosis via salivary microbiota
International Journal of Oral Science, 2022 AbstractThe aim of this study was to identify whether periodontitis induces gut microbiota dysbiosis via invasion by salivary microbes. First, faecal and salivary samples were collected from periodontally healthy participants (PH group, n = 16) and patients with severe periodontitis (SP group, n = 21) and analysed by 16S ribosomal RNA sequencing ...
Jun Bao +7 more
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Dysbiosis of the gut microbiota in disease [PDF]
Microbial Ecology in Health & Disease, 2015 There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy, asthma, metabolic syndrome, cardiovascular ...
Carding, Simon +4 more
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Dysbiosis: The first hit for digestive system cancer
Frontiers in Physiology, 2022 Gastrointestinal cancer may be associated with dysbiosis, which is characterized by an alteration of the gut microbiota. Understanding the role of gut microbiota in the development of gastrointestinal cancer is useful for cancer prevention and gut ...
Si Mei +16 more
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Gut microbiota dysbiosis in AKI to CKD transition
Biomedicine & Pharmacotherapy, 2023 The symptoms of acute kidney injury (AKI) include a sudden drop-in glomerular filtration rate (GFR), a rise in serum creatinine (sCr), blood urea nitrogen (BUN), and electrolytes, which leads to a rapid loss of kidney function. Chronic kidney disease progresses when AKI symptoms persist for over three months or 90 days.
G R, Saranya, Pragasam, Viswanathan
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Gut microbiota and allergic diseases in children
Allergology International, 2022 The gut microbiota resides in the human gastrointestinal tract, where it plays an important role in maintaining host health. The human gut microbiota is established by the age of 3 years.
Shohei Akagawa, Kazunari Kaneko
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Fungal gut microbiota dysbiosis in systemic lupus erythematosus
Frontiers in Microbiology, 2023 IntroductionDespite recent developments in our comprehension of how the gut microbiota and systemic lupus erythematosus (SLE) are related. The mycobiome: which is a small but crucial part of the gut microbiota and is involved in hosts’ homeostasis and physiological processes, remained unexplored in SLE.MethodsWe profiled the gut fungal mycobiota based ...
Ping Yang +9 more
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Frontiers in Microbiology, 2022 Gut microbiota plays an important role in the proper functioning of human organisms, while its dysbiosis is associated with disease in various body organs. Diabetes mellitus (DM) is a set of heterogeneous metabolic diseases characterized by hyperglycemia
Junjun Ye +8 more
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