Results 71 to 80 of about 89,407 (306)

Gut Microbiota Dysbiosis in the Development and Progression of Gastric Cancer

Journal of Oncology, 2022
Objectives. This study aims to explore gut microbiota dysbiosis in the histological stages of gastric cancer (GC). Methods. Feces samples and clinical characteristics were collected from patients with different stages of GC, including 15 superficial gastritis (SG), 13 atrophic gastritis (AG), 8 gastric mucosal atypical hyperplasia (GMAH), and 15 ...
Yingying Miao, Hui Tang, Qizhi Zhai, Lu Liu, Lu Xia, Wenhan Wu, Yue Xu, Jianning Wang   +7 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gut microbiota dysbiosis exaggerates ammonia-induced tracheal injury Via TLR4 signaling pathway

Ecotoxicology and Environmental Safety, 2022
Ammonia is a toxic air pollutant that causes severe respiratory tract injury in animals and humans. Gut microbiota dysbiosis has been found to be involved in the development of respiratory tract injury induced by air pollutants, however, the specific ...
Ying Zhou, Xin Zhao, Minhong Zhang, Jinghai Feng   +3 more
doaj   +1 more source

Human Gut Bacteria and Lipidic Nanoparticles: Particle Composition Predicts Structural Transformation and Bacterial Biocompatibility

Advanced Functional Materials, EarlyView.
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell, Emily L. Gulliver, Livia Salvati Manni, Frithjof Herb, Caitlin Welsh, Samuel C. Forster, Andrew J. Clulow, Wye‐Khay Fong   +7 more
wiley   +1 more source

Harmonizing gut microbiota dysbiosis: Unveiling the influence of diet and lifestyle interventions

Metabolism Open
The gut microbiota, comprising trillions of microorganisms inhabiting the gastrointestinal tract, is essential to human health and disease. Recent research has illuminated the interactions between many components of human physiology and the gut ...
Sharvari S. Pandit, Prabhu Meganathan, Hemamalini Vedagiri   +2 more
doaj   +1 more source

Gut microbiota dysbiosis in infantile cholestatic hepatopathy

Frontiers in Pediatrics
BackgroundCholestatic hepatopathy is common in infants. While many studies link gut microbiota to liver and gallbladder diseases, the relationship between infantile cholestatic hepatopathy (ICH) and gut microbiota remains unclear.MethodsWe collected stool samples from 19 healthy controls and 33 infants with ICH aged ≤3 months, then determined the ...
Yi Zou, Wenhao Ni, Yong Zhou, Yong Zhou, Dan Sun, Feng Chen, Xianyun Li   +6 more
openaire   +3 more sources

Dysbiosis signatures of gut microbiota in coronary artery disease [PDF]

Physiological Genomics, 2018
Gut microbiota dysbiosis has been considered to be an important risk factor that contributes to coronary artery disease (CAD), but limited evidence exists about the involvement of gut microbiota in the disease. Our study aimed to characterize the dysbiosis signatures of gut microbiota in coronary artery disease. The gut microbiota represented in stool
Qi, Zhu, Renyuan, Gao, Yi, Zhang, Dengdeng, Pan, Yefei, Zhu, Xiaohui, Zhang, Rong, Yang, Rong, Jiang, Yawei, Xu, Huanlong, Qin   +9 more
openaire   +2 more sources

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Gu-Ben-Fang-Xiao Decoction Ameliorated Murine Asthma in Remission Stage by Modulating Microbiota-Acetate-Tregs Axis

Frontiers in Pharmacology, 2020
Dysbiosis of gut microbiota is a critical factor in the pathogenesis of asthma. Manipulating gut microbiota is a promising therapeutic intervention in asthma, and is being extensively studied.
Yingmei Dong, Yingmei Dong, Hua Yan, Hua Yan, Xia Zhao, Xia Zhao, Rui Lin, Lili Lin, Lili Lin, Yuanyuan Ding, Yuanyuan Ding, Liwei Liu, Lishun Ren, Lishun Ren, Qiongqiong Xing, Qiongqiong Xing, Jianjian Ji   +16 more
doaj   +1 more source

Characterization of gut microbiota dysbiosis in breast cancer patients. [PDF]

Breast Cancer
Abstract Background While lifestyle factors are known to be associated with breast cancer development, the potential role of the gut microbiome, which is influenced by lifestyle, as a risk factor is not well understood.
Yamada M, Kubo M, Kaneshiro K, Kai M, Morisaki T, Hayashi S, Ochiai Y, Sato Y, Mizoguchi K, Takao Y, Arimura A, Nakamura M.   +11 more
europepmc   +4 more sources