Results 91 to 100 of about 89,407 (306)

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms

, 2011
BACKGROUND: While our knowledge of the intestinal microbiota during disease is accumulating, basic information of the microbiota in healthy subjects is still scarce.
Vos, W.M., de, Willem M de Vos, Immonen, Outi, Janne Nikkilä, de Vos Willem M., Jalanka-Tuovinen, J., Salonen Anne, Lahti Leo, Leo Lahti, Anne Salonen, Jalanka-Tuovinen, Jonna, de Vos, W.M., Airi Palva, Nikkilä Janne, Palva Airi, de Vos, Willem M., Immonen Outi, Kekkonen, Riina, Lahti, Leo, Palva, Airi, Kekkonen Riina, Nikkila, Janne, Jonna Jalanka-Tuovinen, Willem M. de Vos, Jalanka-Tuovinen Jonna, Riina Kekkonen, Outi Immonen, Salonen, Anne   +27 more
core   +1 more source

A Review of the Effects of Natural Compounds, Medicinal Plants, and Mushrooms on the Gut Microbiota in Colitis and Cancer

Frontiers in Pharmacology, 2020
The human gastrointestinal tract harbors a diverse array of microorganisms that play fundamental roles in health and disease. Imbalance in the gut microbiota, namely dysbiosis, can lead to various diseases, including cancer and gastrointestinal tract ...
Man Kit Cheung, Grace Gar Lee Yue, Grace Gar Lee Yue, Philip Wai Yan Chiu, Clara Bik San Lau, Clara Bik San Lau   +5 more
doaj   +1 more source

Lentinan improves intestinal inflammation and gut dysbiosis in antibiotics-induced mice

Scientific Reports, 2022
Gut microbiota dysbiosis is already a global problem after antibiotic overuse. This study was to investigate the therapeutic effect of lentinan and the mechanism of recovery of intestinal inflammation on broad-spectrum antibiotic-driven gut microbial ...
Xiuyu Ji, Le Su, Ping Zhang, Qiulin Yue, Chen Zhao, Xin Sun, Kunlun Li, Xinli Liu, Song Zhang, Lin Zhao   +9 more
doaj   +1 more source

Vancomycin-induced gut microbiota dysbiosis aggravates allergic rhinitis in mice by altered short-chain fatty acids

Frontiers in Microbiology, 2022
ObjectiveThis study aims to explore how gut microbiota dysbiosis affects allergic rhinitis (AR) and whether short-chain fatty acids (SCFAs) play a role in this process.MethodsA mouse gut microbiota dysbiosis model was established by adding vancomycin to ...
Zhen Chen, Zhen Chen, Qingqing Xu, Qingqing Xu, Yang Liu, Yang Liu, Yihan Wei, Yihan Wei, Shancai He, Wei Lin, Wei Lin, Yingge Wang, Yingge Wang, Li Li, Yuanteng Xu, Yuanteng Xu   +15 more
doaj   +1 more source

Gut Dysbiosis and Fecal Microbiota Transplantation in Autoimmune Diseases

International Journal of Molecular Sciences, 2022
Gut microbiota dysbiosis has recently been reported in a number of clinical states, including neurological, psychiatric, cardiovascular, metabolic and autoimmune disorders. Yet, it is not completely understood how colonizing microorganisms are implicated in their pathophysiology and molecular pathways.
Paulina Belvoncikova, Martin Maronek, Roman Gardlik   +2 more
openaire   +2 more sources

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease [PDF]

, 2011
Peer ...
Parkhill Julian, Parkes, Gareth C., Hudspith, Barry N., Gareth C Parkes, Parkes, Gareth C, Sanderson Jeremy D, Parkhill, J, Walker, AW, Jeremy D Sanderson, Jonathan Brostoff, Walker, Alan W., Sanderson, Jeremy D., Hudspith Barry N, Dougan Gordon, Churcher, C, Parkes Gareth C, Brostoff, Jonathan, Neil Rayment, Hudspith, Barry N, Julian Parkhill, Rayment, Neil, Alan W Walker, Brostoff, J, Walker Alan W, Gordon Dougan, Petrovska, L, Liljana Petrovska, Dougan, Gordon, Parkhill, Julian, Parkes, GC, Brostoff Jonathan, Sanderson, Jeremy D, Carol Churcher, Sanderson, JD, Barry N Hudspith, Rayment Neil, Rayment, N, Churcher, Carol, Petrovska, Liljana, Hudspith, BN, Petrovska Liljana, Dougan, G, Churcher Carol, Walker, Alan W   +43 more
core   +1 more source

Dysbiosis of Gut Microbiota in Ankylosing Spondylitis Patients

Journal of Inflammation Research
Ankylosing spondylitis (AS) is a chronic inflammatory disease associated with genetic, immune, and microbial factors. The role of gut microbiota in the pathogenesis of AS is increasingly recognized, with studies suggesting that intestinal dysfunction may trigger systemic inflammation.
Lianjun Yang, Kun Wang, Bin Liu, Tao Chen, Tao Ma, Zhifei Cui, Dawei Zhang, Shiyanjin Zhang, Xiang Liu, Jun Shen, Hai Lu   +10 more
openaire   +4 more sources

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source