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Gut Virome and Inflammatory Bowel Disease. [PDF]
Gut virome has been shown to yield some beneficial effects on humans, being deeply involved in physiology, inflammation, immunity, and disease. Together with transkingdom interactions, it can interplay with genetic variation in the host to establish ...
Franco Scaldaferri +2 more
exaly +6 more sources
The Gut Virome Database Reveals Age-Dependent Patterns of Virome Diversity in the Human Gut [PDF]
The gut microbiome profoundly affects human health and disease, and their infecting viruses are likely as important, but often missed because of reference database limitations. Here, we (1) built a human Gut Virome Database (GVD) from 2,697 viral particle or microbial metagenomes from 1,986 individuals representing 16 countries, (2) assess its ...
Olivier Zablocki +2 more
exaly +3 more sources
Prophages Are Gut Virome Pioneers [PDF]
A recent study shows that assembly of gut viral communities in early life occurs in distinct steps and is modulated by breastfeeding.
Ashley York
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Longitudinal Comparison of the Developing Gut Virome in Infants and Their Mothers [PDF]
The human gut virome and its early life development are poorly understood. Prior studies have captured single-point assessments with the evolution of the infant virome remaining largely unexplored.
Charles Y. Chiu, William A Walters
exaly +2 more sources
Stability of the Human Gut Virome and Effect of Gluten-Free Diet [PDF]
The human gut microbiome consists of bacteria, archaea, eukaryotes, and viruses. The gut viruses are relatively underexplored. Here, we longitudinally analyzed the gut virome composition in 11 healthy adults: its stability, variation, and the effect of a
Jingyuan Fu +2 more
exaly +2 more sources
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Advances and Challenges in Cataloging the Human Gut Virome
Cell Host and Microbe, 2022The human gut virome, which is often referred to as the "dark matter" of the gut microbiome, remains understudied. A better understanding of the composition and variations of the gut virome across populations is critical for exploring its impact on diseases and health.
Junhua Li, Minfeng Xiao
exaly +3 more sources
Enteric Virome and Carcinogenesis in the Gut
Digestive Diseases and Sciences, 2020Colorectal cancer (CRC) is a leading cause of cancer-related deaths in both the USA and the world. Recent research has demonstrated the involvement of the gut microbiota in CRC development and progression. Microbial biomarkers of disease have focused primarily on the bacterial component of the microbiome; however, the viral portion of the microbiome ...
Cade, Emlet +2 more
openaire +2 more sources
The gut virome in inflammatory bowel diseases
Current Opinion in Virology, 2021Dysbiosis of the microbiome has been extensively studied in inflammatory bowel diseases (IBD). The roles of bacteria and fungi have been studied in detail, but viral communities, an important component of the microbiome, have been less thoroughly investigated. Metagenomics provided a way to fill this gap by using DNA sequencing to enumerate all viruses
Guanxiang Liang +3 more
openaire +2 more sources
The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific
The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain uncharacterised and their roles in shaping the gut microbiome and in impacting on human health remain poorly understood.
Feargal J Ryan +2 more
exaly +2 more sources

