Results 221 to 230 of about 247,905 (333)

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

PM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang, Qing Kuang, Cheng Chen, Binru Wang, Wei Xiang, Xinming Li, Jianjiao Mou   +6 more
wiley   +1 more source

Integrating sequence-based GWAS and comparative genomic analysis reveals conservation and species-specificity of putative functional variants influencing tail length and tail abnormalities in pigs and sheep. [PDF]

PLoS One
Zhang X, Mainzer J, Giambra I, Yin T, Engel P, Hümmelchen H, Wagner H, Wehrend A, Egerer C, Gerhards K, Reiner G, König S.   +11 more
europepmc   +1 more source

A Bayesian hierarchical variable selection prior for pathway‐based GWAS using summary statistics

, 2019
Yi Yang, Saonli Basu, Lin Zhang
openalex   +2 more sources

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis [PDF]

, 2018
Sarah E. Graham, Jonas B. Nielsen, Matthew Zawistowski, Wei Zhou, Lars G. Fritsche, Maiken E. Gabrielsen, Anne Heidi Skogholt, Ida Surakka, Damian Fermin, Sachin Kheterpal, Chad M. Brummett, Seunggeun Lee, Hyun Min Kang, Gonçalo R. Abecasis, Solfrid Romundstad, Stein Hallan, Matthew G. Sampson, Kristian Hveem, Cristen J. Willer   +18 more
openalex   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Causal inference and GWAS: Rubin, Pearl, and Mendelian randomization [PDF]

R. J. C. Cantet, Just Jensen
openalex   +1 more source

Past, present and future of local crop evolution

PLANTS, PEOPLE, PLANET, EarlyView.
Promoting agrobiodiversity is a promising strategy for mitigating the negative effects of climate change on global food security. We highlight the central role evolutionary processes play in harnessing the potential of local crops by integrating genomics, archaeology, ethnobotany and traditional ecological knowledge (TEK).
Nataly Allasi Canales, Philippa Ryan, Amy Jackson, Hong Phuong Le, James Borrell, Aaron Davis, Rafal M. Gutaker   +6 more
wiley   +1 more source

The Drosophila Post-mating Response: Gene Expression and Behavioral Changes Reveal Perdurance and Variation in Cross-Tissue Interactions

G3: Genes, Genomes, Genetics, 2020
Nicole R. Newell, Surjyendu Ray, Justin E. Dalton, Julia C. Fortier, Joyce Y. Kao, Peter L. Chang, Sergey V. Nuzhdin, Michelle N. Arbeitman   +7 more
doaj   +1 more source

Psoriasis risk allele function in activated Th1/17 cells with "memory" to antigen exposure. [PDF]

PLoS One
Yunusbayev B, Ryakhovsky S, Altinbaev R, Kislova A, Danilko K, Kraeva L, Yunusbaeva M.   +6 more
europepmc   +1 more source

Identification of Candidate Genes Related to SPAD Value Using Multi-Year Phenotypic Data in Rice Germplasms by Genome-Wide Association Study (GWAS) [PDF]

Donghyun Baek, Tae‐Heon Kim, Chang‐Ju Lee, Xiang Gao, Woo-Geun Park, Suk‐Man Kim   +5 more
openalex   +1 more source