Results 241 to 250 of about 191,618 (313)

Decoding Primary Open-Angle Glaucoma: A Multi-Omics Approach to Identify Druggable Effector Genes. [PDF]

Invest Ophthalmol Vis Sci
Guo J, Yao Y, Lin H, Niu Y, Li X, Liu J, Liu S, Qin Y, Biradar M, Shang X, Zhu Z, Plotnikov D, Wang H, Khawaja AP, He M, Huang Y, Zhang H.   +16 more
europepmc   +1 more source

Obstructive Sleep Apnea and BMI, Body Fat Percentage in the East Asian Population: A Bidirectional and Multivariate Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the causal relationship between obstructive sleep apnea and body fat percentage and body mass index (BMI) in the East Asian population by using bidirectional Mendelian randomization and multivariate Mendelian randomization.
Rui Fan, Wen‐Jun Lu, Hua Zhang, Hai‐Ling Jiang, Tao Li, Yan Yan   +5 more
wiley   +1 more source

The Relationship Between Blood Lipids, Coagulation Indexes, Blood Homocysteine and Sudden Deafness: A Retrospective Study and Mendelian Randomization Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Certain blood components, including blood lipids, coagulation parameters, and homocysteine, have been suggested to correlate with the incidence and prognosis of sudden sensorineural hearing loss (SSNHL). However, the nature of these associations remains controversial.
Feng‐Xin Yang, Yu‐Wan Song, Yan Wang, Kun Zhao, Hu‐Hui‐Fen He, Jing‐Jing Qiu, Da‐Wei Liu, Bo Li, Yan Sun   +8 more
wiley   +1 more source

Systematic Approach for Compound Angus Populations Revealing Positional Candidate Genes and Improving Prediction Accuracy in Carcass Traits. [PDF]

Animals (Basel)
Yu Y, Fu Y, Zhao J, Wu S, Wang S, Li Z, Liu L, Sun F, Zhong J, Wang J, Lan D, Kangzhu Y.   +11 more
europepmc   +1 more source

Effects of Obstructive Sleep Apnea on Personality and Temperament: A Cohort and Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is associated with neurocognitive impairment, but its causal relationship with personality traits remains poorly understood. This study investigates the association and causality between OSA and personality using both cohort and genetic data.
Jian‐Hong Liao, Yun‐Han Shi, Xin‐Peng Xu, Yan‐Ru Li, De‐Min Han   +4 more
wiley   +1 more source

Unraveling the pathogenic mechanisms of osteoarthritis and obesity: An integration of GWAS, cellular specificity, and spatial transcriptomics. [PDF]

Osteoarthr Cartil Open
Lin Z, Wei J, Zhou H.
europepmc   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Large-scale admixture mapping in the All of Us Research Program improves the characterization of cross-population phenotypic differences. [PDF]

Nat Commun
Mandla R, Shi Z, Hou K, Wang Y, Mies G, Aw AJ, Cullina S, Penn Medicine BioBank, Kenny E, Mathieson I, Atkinson EG, Martin AR, Pasaniuc B.   +12 more
europepmc   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source