Results 201 to 210 of about 198,268 (313)

Disulfidptosis‐ and Ferroptosis‐Related Gene Signatures in Rheumatoid Arthritis: Association Analysis and Diagnostic Model Construction

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint damage. Although ferroptosis has been implicated in RA progression, the role of disulfidptosis and its interaction with ferroptosis remains unclear.
Ting‐Ting Wang, Dong‐Mei Wang, Xue Li, Yuan‐Li Wei, Ping‐Dan Liu, Shi‐Lin Li, Si‐Ying Xiong, Cai‐Zhen Liu, Fan‐Xin Zeng, Jian‐Hong Wu, Lin Tang   +10 more
wiley   +1 more source

A review of self-supervised imaging phenotypes for genome-wide association studies. [PDF]

Commun Biol
Patel K, Zhao X, Xie Z, Zhi D.
europepmc   +1 more source

Decoding the Gut‐Brain Axis: Multi‐Omics Reveals a Causal Chain Linking Human Genome, Gut Microbiota, Blood Metabolites, and Alertness in the Brain

Med Research, EarlyView.
This multi‐omics study identified genetic loci, gut microbiota, blood metabolites, and gray matter volumes of orbitofrontal cortex and cerebellum that were potentially relevant to alerting in healthy Chinese adults. Subsequent two‐step one‐sample Mendelian randomization further revealed a serial mediation pathway: Bacteroides intestinalis influences ...
Hongru Li, Chuansheng Chen, Ofir Turel, Yu Pu, Hong Chen, Tingyong Feng, Jiang Qiu, Xu Lei, Qinghua He   +8 more
wiley   +1 more source

GCH1 p.Ser80Asn Confers Risk for Parkinson's Disease in East Asian Populations

Movement Disorders, EarlyView.
Abstract Introduction GCH1 has been implicated in Parkinson's disease (PD), but its risks variants and associations are not well defined. Objectives Our goal was to investigate the clinical relevance and PD risk associated with the GCH1 p.Ser80Asn variant.
Yi Wen Tay, Andrew Leslie Lee, Jie Ping Schee, Chin‐Hsien Lin, Eng King Tan, Jung Hwan Shin, Pin‐Shiuan Chen, Sung‐Pin Fan, Cheng‐Hsuan Li, Ebonne Yu Lin Ng, Han Joon Kim, Beomseok Jeon, Sulev Koks, Huyen Thi Thanh Vu, Kin Ying Mok, Yi Ting Lim, Mohd Salahuddin Kamaruddin, Tzi Shin Toh, Hans Xing Ding, Anis Nadhirah Khairul Anuar, Norlisah Ramli, Ignacio J. Keller Sarmiento, Maria Teresa Periñan, Zih‐Hua Fang, Lara M. Lange, Kishore R. Kumar, Soraya Bardien, Joanne Trinh, Enza Maria Valente, SG10K_Health Consortium, the Global Parkinson's Genetics Program (GP2), Peter Heutink, Katja Lohmann, Christine Klein, Niccolò E. Mencacci, Shen‐Yang Lim, Azlina Ahmad‐Annuar, Ai Huey Tan   +37 more
wiley   +1 more source

Integrative genomic SEM analysis of shared genetic architecture and candidate genes for insulin resistance-related metabolic traits. [PDF]

PLoS One
Li S, Liang Y, Zhu G, Wu L, Li H, Li Y, Chen Q.   +6 more
europepmc   +1 more source

GWAS

Japanese Journal of Allergology, 2016
openaire   +1 more source

M genes as a new frontier in plant protection

New Plant Protection, EarlyView.
Microbiome genes, or M genes, are host genes involved in shaping microbial communities. In plant protection, microbiome engineering via M genes shows great promise for the development of new production strategies in the face of increasing pathogen pressure.
Kathryn De Abreu, Tomislav Cernava
wiley   +1 more source

The Drosophila Post-mating Response: Gene Expression and Behavioral Changes Reveal Perdurance and Variation in Cross-Tissue Interactions

G3: Genes, Genomes, Genetics, 2020
Nicole R. Newell, Surjyendu Ray, Justin E. Dalton, Julia C. Fortier, Joyce Y. Kao, Peter L. Chang, Sergey V. Nuzhdin, Michelle N. Arbeitman   +7 more
doaj   +1 more source

Systematic comparison of phenome-wide admixture mapping and genome-wide association at biobank-scale. [PDF]

Nat Commun
Cullina S, Shemirani R, Shi Z, Mandla R, Pasaniuc B, Asgari S, Kenny EE.   +6 more
europepmc   +1 more source

Functional Characterization of CYP26B1 Short Isoform as a Novel Locus for Obesity in Indigenous Americans From Arizona

Obesity, EarlyView.
ABSTRACT Objective To identify heritable factors that affect BMI among Indigenous Americans, we previously conducted a genome‐wide association study using 7.9 million imputed genetic variants from 6789 participants. This study sought to identify a mechanistic link between variants with the strongest association with BMI and adipocyte metabolism ...
Fehmida Farid Khan, Michael Traurig, Kendrick Freeland, Robert L. Hanson, Paolo Piaggi, Leslie J. Baier   +5 more
wiley   +1 more source