Results 261 to 270 of about 247,905 (333)

Mendelian randomization analysis integrating GWAS and eQTL data identified potential regulatory genes associated with prostate cancer in neural cells [PDF]

Jiahao Guo, Hao Xie, Quanting Yin, Changming Dong, Yufan Yang, Jiazi Cha, Jinshan Yang, Xinxin Li, Yue Li, Fuyi Xu, Chunhua Lin   +10 more
openalex   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, EarlyView.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source

Archipelago Method for Variant Set Association Test Statistics. [PDF]

Genet Epidemiol
Lawless D, Saadat A, Oumelloul MA, Schlapbach LJ, Fellay J.   +4 more
europepmc   +1 more source

A Systems Biology Framework Uncovers Multi-Level Genetic Regulation of Dizziness/vertigo Through eQTL–GWAS Integration and Single-Cell Analysis

Dingduo Shan, Shuo Li, Lili Zhang, Jiaqi Bai, Henglin Wang   +4 more
openalex   +1 more source

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer, Tom P. Freeman, Martine Skumlien, Esther Walton, Thomas Lancaster, Jorien L. Treur, Valentina Lorenzetti, Anna K. M. Blackwell, Chloe Burke, Richie J. Carr, Constantinos Constantinides, Maisie Cox, Sarah Dance, Shadi Daryan, Sorcha Hamilton, Tom Jenkins, Gemma M. J. Taylor   +16 more
wiley   +1 more source

Research note: Integration of GWAS and RNA-seq identifies mutations linked to within feather patterning in domestic chickens. [PDF]

Poult Sci
Guo H, Chen Y, Guo Y, Wang B, Li J.
europepmc   +1 more source

Discovering new genes for alfalfa (Medicago sativa) growth and biomass resilience in combined salinity and Phoma medicaginis infection through GWAS [PDF]

Wiem Mnafgui, Cheima Jabri, Nada Jihnaoui, Nourhene Maiza, Amal Guerchi, Nawres Zaidi, Gerhard Basson, Eden Keyster, Naceur Djébali, Luciano Pecetti, Mohsen Hanana, Paolo Annicchiarico, Muhammet Şakiroğlu, Ndiko Ludidi, Mounawer Badri   +14 more
openalex   +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

Allergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan, Brooke Szczesny, Kanika Kanchan, Erika Esquinca, Meher Preethi Boorgula, Sameer Chavan, Monica Campbell, Wendy Lorizio, Ayo P. Doumatey, Alvaro A. Cruz, Harold Watson, Edward T. Naureckas, B. Louise Giles, Ganiyu Arinola, Olumide Sogaolu, Adegoke G. Falade, Nadia N. Hansel, Christopher O. Olopade, Charles N. Rotimi, R. Clive Landis, Camila A. Figueiredo, Eimear E. Kenny, Ingo Ruczinski, Andrew H. Liu, Carole Ober, Margaret A. Taub, Randi K. Johnson, Kathleen C. Barnes, Genevieve L. Wojcik, Rasika A. Mathias   +29 more
wiley   +1 more source

Genome co-adaptation and the evolution of methicillin resistant Staphylococcus aureus. [PDF]

Genome Biol
Ko S, Cummins EA, Monteith W, Sheppard SK.   +3 more
europepmc   +1 more source