Results 271 to 280 of about 247,905 (333)

Rare non-synonymous genetic variants do not account for susceptibility to primary angle closure glaucoma at eight known common variant GWAS loci.

, 2018
Eranga N. Vithana, Monisha E. Nongpiur, Zheng Li, Shamira Perera, Rahat Husain, Tina Wong, Ching‐Lin Ho, Ching‐Yu Cheng, Tien Yin Wong, Chiea Chuen Khor, Tin Aung   +10 more
openalex   +1 more source

Causal relationship between immune cells and idiopathic thrombocytopenic purpura: A bidirectional Mendelian randomization study

Rheumatology &Autoimmunity, EarlyView.
Heyi Zhang, Luyao Song, Ying Mao, Zerui Liu, Zhexi He, Mengxia Liu, Jingfang Zhang, Rui Zhao, Jing Luo, Shengxiao Zhang   +9 more
wiley   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Cross-Ancestry Polygenic Prediction: Comparing Methods and Assessing Transferability Across Traits. [PDF]

Genet Epidemiol
Momin MM, Zhou X, Ahmed M, Hyppönen E, Benyamin B, Lee SH.   +5 more
europepmc   +1 more source

Genetic, lifestyle and environmental risk factors for chronic pain revealed through GWAS

, 2020
Mischa Lundberg, Adrián I. Campos, Scott F. Farrell, Geng Wang, Michele Sterling, Miguel E. Rentería, Thanh Ngo Trung, Gabriel Cuéllar-Partida   +7 more
openalex   +1 more source

The Testicular Cancer Consortium (TECAC): Filling Knowledge Gaps in the Genetic Etiology of Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The Testicular Cancer Consortium (TECAC) was established in 2012 and is comprised of researchers from over 25 centers in Europe and North America. TECAC's overarching goal is to investigate the genetic susceptibility of testicular germ cell tumors (TGCT) to better understand their biology, impact prevention strategies, and inform ...
Peter A. Kanetsky, Kristian Almstrup, Svetlana Cherlin, Victoria K. Cortessis, Alberto Ferlin, Jourik A. Gietema, Anna González‐Neira, Tom Grotmol, Robert J. Hamilton, Trine B. Haugen, Lambertus A. Kiemeney, Jung Kim, Csilla Krausz, Davor Lessel, Ragnhild A. Lothe, Kevin T. Nead, Jérémie Nsengimana, Jenny N. Poynter, Ewa Rajpert‐DeMeyts, Lorenzo Richiardi, Stephen M. Schwartz, Rolf I. Skotheim, Douglas R. Stewart, Clare Turnbull, Fredrik Wiklund, Tongzhang Zheng, Katherine L. Nathanson, Katherine A. McGlynn, for the Testicular Cancer Consortium   +28 more
wiley   +1 more source

Contribution of rare variation to degenerative orthopedic diseases. [PDF]

Osteoarthr Cartil Open
Anker-Hansen C, Manderstedt E, Lind-Halldén C, Halldén C, Zöller B.   +4 more
europepmc   +1 more source

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source

A resource of “bottom-line” variant associations for 1,281 complex traits by integrating data across published genome-wide association studies

Nguyen T, Büyükgöl F, Smadbeck P, Massung J, Costanzo M, Ruiz M, Dornbos P, Yoshiji S, Koesterer R, Nguyen TL, Jang D, Hoang Q, Ji Y, McMahon A, Sengupta S, Yin X, Ryan B, Welch R, Treur J, Bezzina C, Abecasis GR, Boehnke M, Burtt N, Flannick J.   +23 more
europepmc   +1 more source

Genome-wide detection of superior haplotypes for seed oil and protein content in Northeast China soybean (<i>Glycine max</i> L.) germplasm. [PDF]

Front Plant Sci
Bu M, Zhang Y, Xu W, Li Y, Yu H, Zhang Y, Yang S, Bhat JA, Feng X.   +8 more
europepmc   +1 more source