Results 91 to 100 of about 592,523 (331)

A Nomogram Based on Fibrinogen-to-Neutrophil Ratio as a Novel Predictor of Lymph Node Metastasis in Patients with Cervical Cancer and Type 2 Diabetes Mellitus

Cancer Management and Research
Hongying Kuang,1,* Dongxia Yang,2,* Ruoyao Lin,3 Yaling Tang,4 Yongli Luo,3 Shuwen Wang,5 Tingting Xia,5 Ge Lou,6 Hong Chen4 1Department of Gynecology, The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin ...
Kuang H, Yang D, Lin R, Tang Y, Luo Y, Wang S, Xia T, Lou G, Chen H   +8 more
doaj  

Assisted reproductive technology in Japan: a summary report for 2015 by The Ethics Committee of The Japan Society of Obstetrics and Gynecology

Reproductive Medicine and Biology, 2017
The Japan Society of Obstetrics and Gynecology (JSOG) implemented an assisted reproductive technology (ART) registry system in 1986. Here are reported the characteristics and treatment outcomes of ART cycles that were registered in 2015.
H. Saito, S. Jwa, A. Kuwahara, Kazuki Saito, T. Ishikawa, O. Ishihara, K. Kugu, R. Sawa, K. Banno, M. Irahara   +9 more
semanticscholar   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome

Drug Design, Development and Therapy
Zhenzhen Cao,1,* Qin Zhou,1,* Jie An,1,* Xiaojing Guo,1 XiaoFang Jia,1 Yuena Qiu2 1Department of Gynecology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, Jiangsu, 215300, People’s Republic of China; 2Department of ...
Cao Z, Zhou Q, An J, Guo X, Jia X, Qiu Y
doaj  

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

Advanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui, Xinhang Meng, Yujie Luo, Jinfeng Qian, Fengrun Sun, Mingke Qiu, Songcun Wang   +6 more
wiley   +1 more source

Predicting Infection Risk in Acute Compartment Syndrome: A Nomogram Model Based on Admission Blood Indicators

International Journal of General Medicine
JianJun Song,1 YueJun Liu,2 Meng Yang,3 Yan Li,1 YueYue Hu4 1Emergency ICU, Gynecology Department, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, People’s Republic of China; 2Department of Gynecology, Gynecology Department ...
Song J, Liu Y, Yang M, Li Y, Hu Y
doaj  

Work-Related Musculoskeletal Disorders and Risk Factors among Chinese Medical Staff of Obstetrics and Gynecology

International Journal of Environmental Research and Public Health, 2017
Medical staff in the department of obstetrics and gynecology are a group of professionals reportedly at high risk of work-related musculoskeletal disorders (WMSD), however, little is known about the current status of this problem in China.
Jingjing Wang, Yabin Cui, Lihua He, Xiangrong Xu, Z. Yuan, Xianning Jin, Zhimin Li   +6 more
semanticscholar   +1 more source

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi   +18 more
wiley   +1 more source

Development and evaluation of a “simulator-based” ultrasound training program for university teaching in obstetrics and gynecology–the prospective GynSim study

Frontiers in Medicine
IntroductionThis study addresses the challenges of ultrasound education in obstetrics and gynecology, focusing on the potential benefits of simulation techniques in medical training.
Johannes Weimer, Florian Recker, Annette Hasenburg, Holger Buggenhagen, Karla Karbach, Lia Beer, Andreas Weimer, Lina Schiestl, Liv Lorenz, Roman Kloeckner, Anna Dionysopoulou   +10 more
doaj   +1 more source

Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T‐Cell Function and Anti‐PD‐1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T‐Cell‐Incorporated Tumor Organoid Studies

Advanced Science, EarlyView.
Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren, Junjun Qiu, Fanghua Chen, Qian Jiang, Qinqin Liu, Tong Wu, Hua Jiang, Keqin Hua   +7 more
wiley   +1 more source