Results 31 to 40 of about 11,249 (166)

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

JEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson, Kara Hurley, Hannah Chaudhury, Lara Shehadeh, Cameron West   +4 more
wiley   +1 more source

Endoscope‐Assisted Nipple‐Sparing Mastectomy With Immediate Implant Reconstruction: A Retrospective Study

World Journal of Surgery, EarlyView.
Breast cancer surgery increasingly favors nipple‐sparing and endoscopic techniques to optimize oncological safety, cosmetic outcomes, and patient satisfaction. We aimed to evaluate and compare the clinical efficacy and postoperative safety profiles of endoscope‐assisted and conventional open approaches for nipple‐sparing mastectomy with immediate ...
Yuan Shao, Youcheng Zhang, Huafeng Kang, Qing Zhou, Ziliang Zhang, Guiru Yan, Binghua Kan   +6 more
wiley   +1 more source

Gynecomastia and hypertension in a patient treated with posaconazole

Clinical Case Reports, 2020
Posaconazole therapy may lead to increased serum estradiol levels and development of gynecomastia. Early detection by endocrine hormone measurements may help preventing gynecomastia.
George R. Thompson III, Prasanth N. Surampudi, Alex Odermatt   +2 more
doaj   +1 more source

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor, Oishee Bandyopadhyay, Nahian Ahmed, Kapishan Shanmugathasan, Alice Cotton, ChingHao Chen, Tet Yap   +6 more
wiley   +1 more source

Mineralocorticoid receptor antagonists: Efficacy and safety in chronic kidney disease

Diabetes, Obesity and Metabolism, EarlyView.
Abstract The mineralocorticoid receptor (MR) has a multifaceted role in normal physiologic functions. However, research has uncovered the deleterious consequences of overactivation of the MR. It has been implicated in chronic kidney disease (CKD) via its strong association with glomerulosclerosis, interstitial fibrosis, proteinuria, and decline in ...
Amy K. Mottl, Kamlesh Khunti, Chantal Mathieu   +2 more
wiley   +1 more source

Male gynecomastia linked to antipsychotics: a case report

European Psychiatry
Introduction Gynecomastia refers to the abnormal development of breast tissue in males, often posing a concerning symptom. Often, gynecomastia is associated with multiple factors, including the use of various drugs, notably certain atypical ...
O. Martin-Santiago, P. Martinez.Gimeno, M. Calvo-Valcarcel, C. Alario-Ruiz, B. Arribas-Simon   +4 more
doaj   +1 more source

Patient‐reported outcomes: active surveillance vs radical therapies in low‐risk prostate cancer

BJU International, Volume 137, Issue 4, Page 716-727, April 2026.
Objective To prospectively evaluate functional patient‐reported outcomes (PROs) in patients with low‐risk prostate cancer (PCa) managed with active surveillance (AS), nerve‐sparing radical prostatectomy (NS‐RP), non‐NS‐RP, or radiotherapy (RT). Patients and Methods This multicentre prospective cohort study used data from the Prostate Cancer Outcomes ...
Mulham Al‐Nader, Claudia Kesch, Osama Mahmoud, Boris A. Hadaschik, Jan Fichtner, Guenther Carl, Günter Feick, Martin Burchardt, Volker Zimmermanns, Lukas Prause, Bülent Polat, Andreas Blana, Marcus Horstmann, Matthias Saar, Petra Miglierini, Kinan Almansur, Lukas Hefermehl, Daniel Porres, Inga Peters, Kristina Wiens, Rein Jüri Palisaar, Alexander Winter, Andreas Neisius, Eva‐Maria Kunzmann, Nina Natascha Harke, Christian Bolenz, Mohamad Hatem Albarghouth, Lukas Manka, Mario Kramer, Ferdinand Luger, Thomas Knoll, Jesco Pfitzenmaier, Marko Brock, Julia Schittko, Jens Peter Sommer, Matthias Reichert, Sebastian Lenart, Philipp Huber, Sameh Hijazi, Anna Calderaro, Thomas Hermanns, Jens Tonhauser, Christoph Kowalski, Nora Tabea Sibert   +43 more
wiley   +1 more source

Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency

Clinical Genetics, Volume 109, Issue 4, Page 784-787, April 2026.
We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou, Helen Turner, Deborah Shears, Fredrik Karpe   +3 more
wiley   +1 more source

Influence of Postoperative Finasteride Therapy on Recurrence of Gynecomastia After Mastectomy in Men Taking Finasteride for Alopecia

American Journal of Men's Health, 2019
Finasteride is commonly used for treatment of alopecia. Because finasteride is a cause of gynecomastia, there is concern regarding the continuation of finasteride therapy after mastectomy.
Seung Geun Lee MD, PhD, Pyoung Jae Park MD, PhD, Sung Ryul Lee MD, PhD, Bum Hwan Koo MD, PhD, Geon Young Byun MD, Myoung Jin Kim MD, Hyok Jo Kang MD, Sarang Kim BSN, RN, Beom Seok Oh BSBC, Young Hyun Lee BSDS   +9 more
doaj   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2582-2593, April 2026.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source