Results 101 to 110 of about 13,532,360 (331)

Regulatory assembly of the vacuolar proton pump VOV1-ATPase in yeast cells by FLIM-FRET

, 2010
We investigate the reversible disassembly of VOV1-ATPase in life yeast cells by time resolved confocal FRET imaging. VOV1-ATPase in the vacuolar membrane pumps protons from the cytosol into the vacuole. VOV1-ATPase is a rotary biological nanomotor driven
Batisse, Claire, Boersch, Michael, Boettcher, Bettina, Ernst, Stefan, Zarrabi, Nawid   +4 more
core   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Identification and Functional Analysis of V-ATPaseA and C Genes in Hyphantria cunea

Insects
Vacuolar (H+)-ATPases (V-ATPases) are ATP-driven proton pumps that play multifaceted roles across various organisms. Despite their widespread significance, the functional implications of V-ATPase genes in Hyphantria cunea, an invasive forest pest with a ...
Xiaojie Wang, Dan Zhao, Qian Wang, Yanan Liu, Xiujun Lu, Wei Guo   +5 more
doaj   +1 more source

Nitrogen deprivation induces cross-tolerance of Poa annua callus to salt stress

Biologia Plantarum, 2016
Alternative respiration pathway (AP) is an important pathway which can be induced by environment stresses in plants. In the present study, we show a new mechanism involving the AP in nitrogen deprivation-induced tolerance of Poa annua callus to salt ...
C. Z. Zhao, P. Li, X. M. Wang, P. Li, X. Y. Wang, F. Wang, J. F. Wang, N. Chang, Y. R. Bi   +8 more
doaj   +1 more source

(Pro)renin Receptor and Vacuolar H+−ATPase

The Keio Journal of Medicine, 2012
The (pro)renin receptor [(P)RR] is a molecule that binds prorenin and renin in tissues, leading not only to their activation, but also carrying out intracellular signaling. As a key player in the tissue renin-angiotensin system, (P)RR activation plays an important role in the development of end-organ damage in hypertension and diabetes. One fragment of
openaire   +2 more sources

Papillomavirus E5: the smallest oncoprotein with many functions [PDF]

, 2011
Papillomaviruses (PVs) are established agents of human and animal cancers. They infect cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are consistently associated with cancer of the uterine cervix, but are also involved in the ...
Borzacchiello, G., Campo, M.S., Corteggio, A., Nasir, L., Paolini, F., Roperto, S., Venuti, A.   +6 more
core   +4 more sources

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo [PDF]

, 2013
Cyclic AMP (cAMP) is a ubiquitous second messenger that regulates a variety of essential processes in diverse cell types, functioning via cAMP-dependent effectors such as protein kinase A (PKA) and/or exchange proteins directly activated by cAMP (EPAC ...
Akbari, Baillie, Beyenbach, Beyenbach, Bos, Bos, Bos, Brand, Börner, Cabrero, Chepurny, Coast, Coast, Coast, Coast, Dames, Davies, Day, de Rooij, Dow, Dow, Dow, Dow, Enserink, Evans, Gloerich, Guo, Hallows, Hector, Iijima–Ando, Johnson, Johnson, Kalderon, Kandel, Kaufmann, Kaupp, Kerr, Laroche–Joubert, MacPherson, O'Donnell, O'Donnell, Parks, Pastor–Soler, Pastor–Soler, Poulsen, Radford, Rein, Rosay, Ryu, Ryu, Schröder–Lang, Stierl, Stokman, Sözen, Terhzaz, Terhzaz, Torrie, Weissenberger, Wong, Zaccolo, Zaccolo   +60 more
core   +1 more source

Saccharomyces cerevisiae Vacuolar H+-ATPase Regulation by Disassembly and Reassembly: One Structure and Multiple Signals

Eukaryotic Cell, 2014
Vacuolar H+-ATPases (V-ATPases) are highly conserved ATP-driven proton pumps responsible for acidification of intracellular compartments. V-ATPase proton transport energizes secondary transport systems and is essential for lysosomal/vacuolar and ...
K. Parra, Chun-Yuan Chan, Jun Chen
semanticscholar   +1 more source

Cytosolic Glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease [PDF]

, 2019
A new paradigm for Niemann-Pick C disease is presented where lysosomal storage leads to a deficit in cytoplasmic glucosylceramide (GlcCer) where it performs important functions.
Bhardwaj, Meenakshi, Haberkant, Per, Schmid, Ralf, Sillence, Daniel J., Tongue, Paige, Wheeler, S.   +5 more
core   +1 more source