Frontiers in Microbiology, 2021 The vacuole of Candida albicans plays a significant role in many processes including homeostasis control, cellular trafficking, dimorphic switching, and stress tolerance.
Quanzhen Lv, Lan Yan, Yuanying Jiang
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A proteomic and phosphoproteomic analysis of Oryza sativa plasma membrane and vacuolar membrane [PDF]
, 2008 Proteomic and phosphoproteomic analyses of rice shoot and root tonoplast-enriched and plasma membrane-enriched membrane fractions were carried out to look at tissue-specific expression, and to identify putative regulatory sites of membrane transport ...
Ahn +38 more
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Cell Reports, 2017 Vacuolar H+-ATPase (v-ATPase) is a multi-subunit complex comprising two domains: the cytosolic V1 domain catalyzing ATP hydrolysis and the membranous V0 sector translocating protons across membranes.
Anna Bodzęta +2 more
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Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer [PDF]
, 2012 Cancer cells show a metabolic shift that makes them overproduce protons; this has the potential to disturb the cellular acid-base homeostasis. However, these cells show cytoplasmic alkalinisation, increased acid
Hernández López, Agustín +3 more
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Estimating the Rotation Rate in the Vacuolar Proton-ATPase in Native Yeast Vacuolar Membranes [PDF]
, 2012 The rate of rotation of the rotor of the yeast vacuolar proton-ATPase (V-ATPase), relative to the stator or the steady parts of enzyme, is estimated in native vacuolar membrane vesicles of Saccharomyces cerevisiae under standardised conditions.
Bóta, A. +9 more
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Understanding the apparent stator-rotor connections in the rotary ATPase family using coarse-grained computer modeling [PDF]
, 2014 Advances in structural biology, such as cryo-electron microscopy (cryo-EM) have allowed for a number of sophisticated protein complexes to be characterized.
Balakrishna +40 more
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Subcellular distribution of the V-ATPase complex in plant cells, and localisation of the 100 kDa subunit VHA-a within the complex [PDF]
, 2004 Background Vacuolar H+-ATPases are large protein complexes of more than 700 kDa that acidify endomembrane compartments and are part of the secretory system of eukaryotic cells. They are built from 14 different (VHA)-subunits.
Kluge Christoph +9 more
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Antifungal mechanism of action of lactoferrin: Identification of H+-ATPase (P3A-type) as a new apoptotic-cell membrane receptor [PDF]
, 2016 Human lactoferrin (hLf) is a protein of the innate immune system which induces an apoptotic-like process in yeast. Determination of the susceptibility to lactoferrin of several yeast species under different metabolic conditions, respiratory activity ...
Acosta Zaldívar, Maikel +2 more
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A cell-based assay for CD63-containing extracellular vesicles [PDF]
, 2019 Extracellular vesicles (EVs) are thought to be important in cell-cell communication and have elicited extraordinary interest as potential biomarkers of disease. However, quantitative methods to enable elucidation of mechanisms underlying release are few.
Cashikar, Anil G, Hanson, Phyllis I
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Organelle-specific isoenzymes of plant V-ATPase as revealed by in vivo-FRET analysis [PDF]
, 2008 Background The V-ATPase (VHA) is a protein complex of 13 different VHA-subunits. It functions as an ATP driven rotary-motor that electrogenically translocates H+ into endomembrane compartments.
Thorsten Seidel +4 more
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