Apical endosomes isolated from kidney collecting duct principal cells lack subunits of the proton pumping ATPase. [PDF]
Endocytic vesicles that are involved in the vasopressin-stimulated recycling of water channels to and from the apical membrane of kidney collecting duct principal cells were isolated from rat renal papilla by differential and Percoll density gradient ...
Ausiello, DA +6 more
core
Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy [PDF]
The vacuolar ATPases are ATP-dependent proton pumps whose functions include the acidification of intracellular compartments and the extrusion of protons through the cell cytoplasmic membrane.
Enrico P Spugnini +3 more
core +1 more source
The multidimensional regulation roles and mechanisms of calcium in fruit quality
This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang +6 more
wiley +1 more source
Interaction of dibutyltin-3-hydroxyflavone bromide with the 16 kDa proteolipid indicates the disposition of proton translocation sites of the vacuolar ATPase [PDF]
The organotin complex dibutyltin-3-hydroxyflavone bromide [Bu2Sn(of)Br] has been shown to bind to the 16 kDa proteolipid of Nephrops norvegicus, either in the form of the native protein or after heterologous expression in Saccharomyces and assembly into a hybrid vacuolar H+-ATPase.
G, Hughes +5 more
openaire +2 more sources
コウボ エキホウマク ATPase ノ コウゾウ ト キノウ [PDF]
The yeast vacuolar membrane H+-ATPase (V-ATPase) is the first member of "vacuolar type" ATPase family that has been successively identified in various endocytic and exocytic membrane compartments of eukaryotic cells.
Yasuhiro Anraku +2 more
core
Overlap between Fe and Zn responsive gene regulatory networks (GRNs) were found, indicative of micronutrient crosstalk, and conservation of root and leaf GRNs and genes suggests strong constraint on homeostasis networks in plants. Abstract Micronutrient stress impacts growth, biomass production, and grain yield in crops.
A. Mishra +11 more
wiley +1 more source
N-terminal chimaeras with signal sequences enhance the functional expression and alter the subcellular localization of heterologous membrane-bound inorganic pyrophosphatases in yeast [PDF]
Expression of heterologous multispanning membrane proteins in Saccharomyces cerevisiae is a difficult task. Quite often, the use of multicopy plasmids where the foreign gene is under the control of a strong promoter does not guarantee efficient ...
Drake García, Rocío +2 more
core +3 more sources
Imaging and 3D reconstruction of membrane protein complexes by cryo-electron microscopy and single particle analysis [PDF]
Cryo-electron microscopy (cryo-EM) in combination with single particle image processing and volume reconstruction is a powerful technology to obtain medium-resolution structures of large protein complexes, which are extremely difficult to crystallize and ...
Gregorini, Marco
core +1 more source
Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley +1 more source
Integral membrane pyrophosphatases : A novel drug target for human pathogens? [PDF]
Membrane-integral pyrophosphatases (mPPases) are found in several human pathogens, including Plasmodium species, the protozoan parasites that cause malaria.
Adrian Goldman +4 more
core +3 more sources

