Results 61 to 70 of about 2,525 (167)
Proton-translocating ATPase from bovine kidney medulla: partial purification and reconstitution
, 1988 The proton-translocating ATPase that is responsible both for urinary and vacuolar acidification was partially purified from bovine kidney medulla microsomes.
S. Gluck, J. Caldwell
core +1 more source
Turkish Journal of Botany, 2011 Boron is an essential micronutrient for plants and animals; however, it can be toxic when present at high concentrations. The purpose of this study was to understand the mechanisms of boron tolerance in the Turkish barley (Hordeum vulgare) Anadolu cultivar.
Atik, Ahmet Emin +6 more
openaire +2 more sources
Structure, subunit function and regulation of the coated vesicle and yeast vacuolar (H+)-ATPases
, 2002 The vacuolar (H+)-ATPases (or V-ATPases) are ATP-dependent proton pumps that function to acidify intracellular compartments in eukaryotic cells. This acidification is essential for such processes as receptor-mediated endocytosis, intracellular targeting ...
Forgac, Michael +5 more
core +1 more source
, 2013 A. Plasma membrane ATPases (Pma). Gene phylogeny (above) of homologues from Hortaea werneckii (HwPma), Mycosphaerella graminicola (MgPma1: XP_003852209.1) and Saccharomyces cerevisiae (Pma1: YGL008C, Pma2: YPL036W), rooted by a homologue from ...
Inanc Birol (277074) +9 more
core +1 more source
Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer [PDF]
, 2012 Cancer cells show a metabolic shift that makes them overproduce protons; this has the potential to disturb the cellular acid-base homeostasis. However, these cells show cytoplasmic alkalinisation, increased acid
Hernández López, Agustín +3 more
core +1 more source
Journal of Cell Science, 1996 ABSTRACT We have investigated the effects of Concanamycin A (CMA), a specific inhibitor of vacuolar type H+-ATPases, on acidification and function of the endo-lysosomal and contractile vacuole (CV) systems of D. discoideum. This drug inhibited acidification and increased the pH of endo-lysosomal vesicles both in vivo and in vitro in a ...
Temesvari, Lesly A. +4 more
openaire +3 more sources
Structure of the Vacuolar H⁺-ATPase Rotary Motor Reveals New Mechanistic Insights [PDF]
, 2015 Vacuolar H+-ATPases are multisubunit complexes that operate with rotary mechanics and are essential for membrane proton transport throughout eukaryotes.
Trinick, J +15 more
core +1 more source
Vacuolar and Plasma Membrane Proton-Adenosinetriphosphatases
, 1999 The vacuolar H+-ATPase (V-ATPase) is one of the most fundamental enzymes in nature. It functions in almost every eukaryotic cell and energizes a wide variety of organelles and membranes.
William R. Harvey, Nathan Nelson
core +1 more source
International Journal of Molecular SciencesThe vacuolar proton-translocating ATPase (V-ATPase) is a transmembrane multi-protein complex fundamental in maintaining a normal intracellular pH. In the tumoral contest, its role is crucial since the metabolism underlying carcinogenesis is mainly based on anaerobic glycolytic reactions.
Martina Giambra +14 more
openaire +2 more sources
Three proton-pumping ATPases in yeast.
, 1986 Yeast cells contain three distinct proton-pumping ATPases associated with the mitochondrial, vacuolar or plasma membranes.
Boutry, Marc, Goffeau, André
core