Results 71 to 80 of about 2,525 (167)

Protein kinase C activation accelerates proton extrusion by vacuolar-type H+-ATPases in murine peritoneal macrophages

, 1994
The role of protein kinase C in the regulation of vacuolar-type H+-ATPase (V-ATPase) activity was studied in thioglycolate-elicited mouse peritoneal macrophages.
Brisseau, Guy F., Grinstein, Sergio, Morris F. Manolson, Rotstein, Ori D., Ori D. Rotstein, Manolson, Morris F., Nordström, Tommy, Tommy Nordström, Sergio Grinstein, Guy F. Brisseau   +9 more
core   +1 more source

Vacuolar proton pumping: more than the sum of its parts? [PDF]

, 2014
Petunia flower colour is dependent on vacuolar pH and is therefore used to study acidification mechanisms. Recently, it was shown that the concerted action of two tonoplast-localised P3-ATPases is required to hyperacidify vacuoles of petunia petal ...
Eisenach, Cornelia, Martinoia, Enrico, Baetz, Ulrike   +2 more
core   +1 more source

Vanadate inhibits vacuolar H+-ATPase-mediated proton transport in chicken kidney microsomes by an ADP-dependent mechanism

, 1996
Recent reports indicate that vacuolar-type proton ATPases from chicken osteoclasts (Chatterjee et al. (1992) Proc. Natl. Acad. Sci. USA 89, 6257–6261), yeast vacuoles and chromaffin granules (Beltran and Nelson (1992) Acta Physiol. Scand. Suppl.
Pe'er David, William C. Home, Baron, Roland, David, Pe'er, Home, William C., Roland Baron   +5 more
core   +1 more source

The Toxoplasma Vacuolar H+-ATPase Regulates Intracellular pH and Impacts the Maturation of Essential Secretory Proteins

, 2019
Summary: Vacuolar-proton ATPases (V-ATPases) are conserved complexes that couple the hydrolysis of ATP to the pumping of protons across membranes. V-ATPases are known to play diverse roles in cellular physiology. We studied the Toxoplasma gondii V-ATPase
Beejan Asady, Nathan M. Chasen, Eric J. Dykes, Stephen A. Vella, Vincent J. Starai, Silvia N.J. Moreno, Andrew J. Stasic   +6 more
core   +1 more source

Study of the Yeast Vacuolar-type ATPase by Electron Cryomicroscopy

, 2016
Vacuolar-type ATPases (V-ATPases) are rotary enzymes that use energy from hydrolysis of adenosine triphosphate (ATP) to pump protons across membranes and control the pH of many intracellular compartments. ATP hydrolysis in the soluble catalytic region of
Zhao, Jianhua
core   +1 more source

Localization of subunit C (Vma5p) in the yeast vacuolar ATPase by immuno electron microscopy

, 2006
Vacuolar ATPases (V1V0-ATPases) function in proton translocation across lipid membranes of subcellular compartments. We have used antibody labeling and electron microscopy to define the position of subunit C in the vacuolar ATPase from yeast.
Forgac, Michael, Zhang, Zhenyu, Inoue, Takao, Wilkens, Stephan   +3 more
core   +1 more source

TRANSPARENT TESTA 13 is a tonoplast P3A -ATPase required for vacuolar deposition of proanthocyanidins in Arabidopsis thaliana seeds.

, 2015
Summary Intracellular pH homeostasis is essential for all living cells. In plants, pH is usually maintained by three structurally distinct and differentially localized types of proton pump: P-type H+-ATPases in the plasma membrane, and multimeric ...
Appelhagen, I., Appelhagen, Ingo, Spelt, C.E., Quattrochio, F., Sagasser, M., Nordholt, Niclas, Koes, Ronald, Weisshaar, Bernd ; https://orcid.org/, Spelt, K., Koes, R., Quattrocchio, F.M., Spelt, Kees, Koes, R.E., Sagasser, Martin ; https://orcid.org/, Seidel, T., Weisshaar, B., Seidel, Thorsten, Nordholt, N., Quattrochio, Francesca   +18 more
core   +1 more source

In situ analysis of pH gradients in mosquito larvae using non-invasive, self-referencing, pH-sensitive microelectrodes

, 2001
The alkaline environment, pH approximately 11, in the anterior midgut lumen of mosquito larvae is essential for normal nutrition and development. The mechanism of alkalization is, however, unknown.
Moroz, L.L., Smith, P.J., Linser, P.J., Boudko, D.Y., Trimarchi, J.R., Harvey, W.R.   +5 more
core  

Vacuolar-type H+-ATPase in mouse bladder epithelium is responsible for urinary acidification

, 1997
The urine in the mouse bladder was found to be acidic, ranging from pH 5.3 to 5.5 in the daytime and pH 6.0 to 6.3 at night. Administration of bafilomycin A1 or concanamycin A, specific inhibitors of vacuolar-type H+-ATPase, into bladder lumen caused ...
Yoshinori Moriyama, Futai, Masamitsu, Shinoda, Sumio, Tomochika, Ken-ichi, Moriyama, Yoshinori, Sumio Shinoda, Ken-ichi Tomochika, Masaharu Mori, Masamitsu Futai, Kumon, Hiromi, Hiromi Kumon, Mori, Masaharu   +11 more
core   +1 more source

Identification of a domain in the V0 subunit d that is critical for coupling of the yeast vacuolar proton-translocating ATPase.

The Journal of biological chemistry, 2006
Vacuolar proton-translocating ATPase pumps consist of two domains, V(1) and V(o). Subunit d is a component of V(o) located in a central stalk that rotates during catalysis. By generating mutations, we showed that subunit d couples ATP hydrolysis and proton transport.
Margaret A, Owegi, Donald L, Pappas, Mark W, Finch, Sarah A, Bilbo, Cruz A, Resendiz, Lori J, Jacquemin, Aswathy, Warrier, John D, Trombley, Kathryn M, McCulloch, Katrina L M, Margalef, Melissa J, Mertz, Jason M, Storms, Craig A, Damin, Karlett J, Parra   +13 more
openaire   +1 more source