Results 91 to 100 of about 2,525 (167)

Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer

, 2019
Cancer cells show a metabolic shift that makes them overproduce protons; this has the potential to disturb the cellular acid-base homeostasis. However, these cells show cytoplasmic alkalinisation, increased acid extrusion and endosome-dependent drug ...
Hernández, Agustín, Serrano-Bueno, Gloria, Serrano, Aurelio, Pérez-Castiñeira, J. R.   +3 more
core  

Vacuolar ATPase regulates ureteric bud branching morphogenesis during kidney development. [PDF]

Am J Physiol Regul Integr Comp Physiol
Yosypiv IV, Liu H, Nakhoul NL.
europepmc   +1 more source

The Roles of Alix and VPS4A in Autophagy and Endosomal Pathways and Their Relation to HBV Replication. [PDF]

FASEB J
Li J, Kemper T, Tong S, Wang X, Lin Y, Lu M.   +5 more
europepmc   +1 more source

Anticancer effects of the V-ATPase inhibitor Archazolid B [PDF]

, 2011
Wiedmann, Romina Madeleine
core  

Bone-in-bone and sandwich vertebrae in a 6-month-old infant with genetically confirmed fatal osteopetrosis: A case report. [PDF]

Medicine (Baltimore)
Hou F, Zhang J.
europepmc   +1 more source

V-ATPase Disassembly at the Yeast Lysosome-Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging. [PDF]

Aging Cell
Hashmi F, Kane PM.
europepmc   +1 more source

Maturation stage-specific V-ATPase disassembly explains the neutral pH of mature mucocyst lysosome-related organelles in Tetrahymena thermophila. [PDF]

J Cell Sci
Pradhan A, Tadasare N, Sarkar D, Maurya V, Bansal LK, Turkewitz AP, Kumar S.   +6 more
europepmc   +1 more source

Life at acidic pH imposes an increased energetic cost for a eukaryotic acidophile

, 2005
Organisms growing in acidic environments, pH <3, would be expected to possess fundamentally different molecular structures and physiological controls in comparison with similar species restricted to neutral pH.
Jung, Sung-Kwon, Zettler, Erik, Messerli, Mark A., Sogin, Mitchell L., Amaral-Zettler, Linda A., Smith, Peter J.S.   +5 more
core  

Identification of the mammalian VPS4A as a selective lipophagy receptor. [PDF]

Autophagy
Dialynaki D, Klionsky DJ.
europepmc   +1 more source

Clinical, morphological, and molecular characterization of patients with X-linked myopathy with excessive autophagy (XMEA). [PDF]

J Neuropathol Exp Neurol
Merlet AN, Lacène E, Nelson I, Brochier G, Labasse C, Chanut A, Madelaine A, Beuvin M, Bonne G, Féasson L, Minot MC, Noury JB, Fradin M, Savarese M, Fernández-Eulate G, Behin A, Stojkovic T, Hentschel A, Marcorelles P, Roos A, Evangelista T.   +20 more
europepmc   +1 more source