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Vacuolar H+-ATPase Signaling in Cancer
2015The vacuolar H+-ATPase (V-ATPase) is an electrogenic H+ pump responsible for the regulation of pH in endomembranous compartments; and for the extrusion of H+ across the plasma membrane in certain cell types, including metastatic cells. The study of the regulation of V-ATPase has been daunting.
Raul Martínez-Zaguilán +1 more
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1981
F.J.M. van de Ven +3 more
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F.J.M. van de Ven +3 more
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Vacuolar H(+)-ATPase in the kidney.
Journal of nephrology, 2002Proton-translocating vacuolar ATPases (H+V-ATPase) are increasingly recognized as essential components of most eukaryotic cells. This electrogenic transporter is present in the cell membranes of many differentiated cell types and in the membranes of many subcellular organelles.
Nazih L, Nakhoul, L Lee, Hamm
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1983
J.J. Schrijen +4 more
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J.J. Schrijen +4 more
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Congruence between PM H+-ATPase and NADPH oxidase during root growth: a necessary probability
Protoplasma, 2018Arkajo Majumdar, R. K. Kar
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Structure and Regulation of Plant Vacuolar H+-ATPase
2008The vacuolar proton translocating ATPase (V-ATPase) is an essential protein complex present in all eukaryotes which functions as ATP-driven rotary motor. In higher eukaryotes, the V-ATPase consists of 13 different subunits. The V-ATPase assembly occurs at the stage of the ER and the presence of isogenes enables the formation of multiple V-ATPase ...
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[H(+)-ATPase and H(+), K(+)-ATPase].
Nihon rinsho. Japanese journal of clinical medicine, 1992Two different types of proton transporting ATPases, v-and p-type H(+)-ATPases engage in epithelial ion transport. Properties, function, molecular structure and distribution of these H(+)-ATPase (v-type) and H+, K(+)-ATPase (p-type) are summarized here. Intraorganellar spaces, such as lysosome, synapse, multivesicular body, are acidified by the vacuole ...
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