Results 11 to 20 of about 6,902 (197)

Teclistamab in Elderly Patients With Relapsed/Refractory Multiple Myeloma: A Subgroup Analysis of the French RetrosTECtive Cohort. [PDF]

EJHaem
ABSTRACT Introduction Real‐world data on teclistamab in relapsed or refractory multiple myeloma (R/R MM), particularly in elderly patients, remain limited. Methods We analysed efficacy and safety outcomes in patients ≥ 75 years from the French RetrosTECtive cohort.
Coste A, Godet S, Manier S, Eveillard JR, Croizier C, Mariette C, Breal C, Manjra H, Touzeau C, Mohty M, Belkhir R, Bobin A, Lévêque A, Cherel B, Montes L, Orsini-Piocelle F, Frenzel L, Robu D, Chalayer E, Harel S, Vincent L, Bauschert L, Dony A, Tabrizi R, Moreau P, Hulin C, Perrot A.   +26 more
europepmc   +2 more sources

Inflammatory disorders in IDH-mutated myeloid neoplasms: Characteristics and response to IDH inhibitors. [PDF]

Hemasphere
HemaSphere, Volume 9, Issue 11, November 2025.
Stammler R, Chen P, Debeaupuis O, Zhao LP, Ruyer-Thompson M, Zakine E, Rossignol J, Goldwirt L, Comont T, Heiblig M, Adès L, Sebert M, Allain JS, Campagne J, Couturier MA, Cumin M, Dalmas MC, Denis G, Devloo C, De Voeght A, Drevon L, Duffau P, Georgin-Lavialle S, Gobert D, Kosmider O, Rieux-Laucat F, Abisror N, Lazaro E, Lopez JG, Maria A, Mauhin W, Merindol J, Merlot C, Mirault T, Pascal L, Perrin F, Raffoux E, Rahme R, Roos-Weil D, Terrier B, Thoreau B, Fain O, Fenaux P, Hirsch P, Jachiet V, Hadjadj J, Mékinian A, MINHEMON.   +47 more
europepmc   +2 more sources

Efficacy and safety of luspatercept with or without erythropoiesis-stimulating agent in patients with myelodysplastic neoplasms with ring sideroblasts: A multicentre real-life study by the GFM. [PDF]

Br J Haematol
British Journal of Haematology, Volume 207, Issue 3, Page 1122-1126, September 2025.
D'Aveni M, Schenone L, Torregrosa JM, Pardo J, Stamatoullas A, Saillard C, Thépot S, Dimicoli S, Santana C, Daguindau E, Paul F, Le Clech L, Park S, Cluzeau T, Paubelle E, Taksin-Bressot AL, Chermat F, Adès L, Fenaux P, Comont T.   +19 more
europepmc   +2 more sources

Ruxolitinib and Hydroxycarbamide Are the Most Efficient Drugs to Reduce Aquagenic Pruritus Intensity in a Real-Word Cohort of Patients With Myeloproliferative Neoplasms. [PDF]

EJHaem
ABSTRACT Background Aquagenic pruritus (AP) is a common and distressing symptom in myeloproliferative neoplasm (MPN) patients. Methods This study assessed cytoreductive therapy effectiveness using data from 489 patients in the OBENE Observatory (NCT02897297). AP severity was tracked regularly after diagnosis.
Gall-Ianotto CL, Civi L, Pan-Petesch B, Herbreteau L, Rio L, Lambert WC, Misery L, Lippert E, Ianotto JC.   +8 more
europepmc   +2 more sources

Real-world study of the efficacy and safety of belantamab mafodotin (GSK2857916) in relapsed or refractory multiple myeloma based on data from the nominative ATU in France: the IFM 2020-04 study

Haematologica, 2023
Belantamab mafodotin (BM) is an anti-BCMA antibody-drug conjugate (GSK2857916) that represents an alternative option in multiple myeloma. We sought to assess the efficacy and safety of BM in a real-world setting in patients who benefited from an early ...
Alexis Talbot, Arthur Bobin, Léa Tabone, Jérôme Lambert, Catherine Boccaccio, Cécile Deal, Marie-Odile Petillon, Olivier Allangba, Philippe Agape, Pierre Arnautou, Rakiba Belkhir, Sylvie Cailleres, Driss Chaoui, Marie-Lorraine Chrétien, Olivier Decaux, Samantha Schulmann, Laurent Frenzel, Lauris Gastaud, Antoine Huart, Cyrille Hulin, Lionel Karlin, Kamel Laribi, Ronan Le Calloch, Pascal Lenain, Margaret Macro, Salomon Manier, Lydia Montes, Stéphane Moreau, Philippe Moreau, Véronique Morel, James Norwood, Frédérique Orsini Piocelle, Aurore Perrot, Gian Matteo Pica, Philippe Rey, Anna Schmitt, Anne-Marie Stoppa, Mourad Tiab, Cyrille Touzeau, Valérie Vidal, Marguerite Vignon, Laure Vincent, Zoé Van De Wyngaert, Charles Zarnitsky, Naima Kerbouche, Prani Paka, Xavier Leleu, Bertrand Arnulf, Hervé Avet-Loiseau, IFM: Intergroupe Francophone du Myélome   +49 more
doaj   +1 more source

Allogeneic transplantation in acute myelogenous leukemia: a comprehensive single institution's experience

Haematologica, 2023
Debates on the role and timing of allogeneic hemtopoietic stem cell transplantation (HSCT) in acute myelogenous leukemia (AML) have persisted for decades.
Gerard Socie, Jacques-Emmanuel Galimard, Emmanuel Raffoux, Raphael Itzykson, Pierre Edouard Debureaux, David Michonneau, Etienne Lengliné, Marie Robin, Flore Sicre de Fontbrune, Marie Sébert, Aliénor Xhaard, Rathana Kim, Anne Couprie, Nathalie Dhedin, Matteo Dragani, Pierre Lemaire, Lise Larcher, Emmanuelle Clappier, Nicolas Boissel, Jean Soulier, Hervé Dombret, Pierre Fenaux, Régis Peffault de Latour, Lionel Adès   +23 more
doaj   +1 more source

Pure Red Cell Aplasia Associated With Thymic Tumors, a Nationwide Retrospective Study. [PDF]

Am J Hematol
ABSTRACT Pure red cell aplasia (PRCA) is the most frequent autoimmune cytopenia associated with thymic tumors (TTs). In a nationwide retrospective study, we included 41 patients (22 women, median age 62 years). At PRCA diagnosis, the mean hemoglobin level was 6.6 ± 2.1 g/dL, and the reticulocyte count was 6 ± 5 × 109/L. PRCA was diagnosed before TT (8%,
Hemmer M, Moinard S, Lambotte O, Malphettes M, Terriou L, Lioger B, Le Guenno G, Viallard JF, Michel M, Lobbes H.   +9 more
europepmc   +2 more sources

Profil Hématologique et Biochimique du Paludisme Grave dans le service d’Hématologie de l’Hôpital National Ignace Deen de Conakry.

Revue Malienne d’Infectiologie et de Microbiologie, 2022
Introduction: Le paludisme est une érythropathie parasitaire due à des protozoaires du genre plasmodium. C'est de loin la parasitose qui touche le plus grand nombre de personnes et provoque le plus de décès . Le but de cette étude était de déterminer les
Mamady Diakite, et. al
doaj   +2 more sources

Cerebral venous thrombosis in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma during induction chemotherapy with l-asparaginase: The GRAALL experience [PDF]

, 2015
International audienceCentral nervous system (CNS) thrombotic events are a well-known complication of acute lymphoblastic leukemia (ALL) induction therapy, especially with treatments including l-asparaginase (l-ASP).
Bonmati, Caroline, Bories, Pierre, Cacheux, Victoria, Chevallier, Patrice, Couturier, Marie-Anne, Daguindau, Etienne, Dombret, Hervé, Dorvaux, Véronique, Escoffre-Barbe, Martine, Frayfer, Jamile, Huguet, Françoise, Hunault-Berger, Mathilde, Ifrah, Norbert, Lhéritier, Véronique, Orvain, Corentin, Pignon, Jean-Michel, Reman, Oumedaly, Sanhes, Laurence, Suarez, Felipe, Tanguy-Schmidt, Aline, Thomas, Xavier   +20 more
core   +4 more sources

Efficiency of nilotinib to target chronic phase-chronic myeloid leukaemia primary mature CD34− and immature CD34+ cells

Scientific Reports, 2021
Accumulation in target cells is an essential pharmacokinetic step of targeted therapies. Tyrosine Kinase Inhibitors (TKI) against the BCR-ABL fusion protein in Chronic Phase-Chronic Myeloid Leukaemia (CP-CML) cells constitute a unique model in terms of ...
Marc G. Berger, Benjamin Lebecque, Thomas Tassin, Louis-Thomas Dannus, Juliette Berger, Mélanie Soucal, Agnès Guerci, Pascale Cony-Makhoul, Hyacinthe Johnson, Gabriel Etienne, Denis Guyotat, Marie-Claude Gagnieu, Bruno Pereira, Sandrine Saugues, Olivier Tournilhac, Eric Hermet, Céline Bourgne   +16 more
doaj   +1 more source