Results 21 to 30 of about 19,699 (145)

Humanized mice for investigating sustained Plasmodium vivax blood-stage infections and transmission

Nature Communications, 2022
Plasmodium vivax is the most widespread human malaria parasite but due to its tropism for immature red blood cells in vitro culturing and studies are difficult. Here, LuizaBatista et al.
Camilla Luiza-Batista, Sabine Thiberge, Malika Serra-Hassoun, Flore Nardella, Aurélie Claës, Vanessa C. Nicolete, Pierre-Henri Commère, Liliana Mancio-Silva, Marcelo U. Ferreira, Artur Scherf, Sylvie Garcia   +10 more
doaj   +1 more source

Un nouveau processus d’interaction hôte-parasite découvert

, 2015
Dans le cas de l’orobanche, plante parasite des cultures, des mécanismes facilitant son développement ont été mis à jour, avec la découverte d’une nouvelle catégorie d’hôte et d’un nouveau processus d’interaction hôte-parasite, la «facilitation».
Simonin, Gérard, Gibot-Leclerc, Stéphanie   +1 more
core   +3 more sources

Resolution therapy: Harnessing efferocytic macrophages to trigger the resolution of inflammation

Frontiers in Immunology, 2022
Several chronic inflammatory diseases are associated with non-resolving inflammation. Conventional anti-inflammatory drugs fail to completely cure these diseases.
Philippe Saas, Mathieu Vetter, Melissa Maraux, Francis Bonnefoy, Francis Bonnefoy, Sylvain Perruche, Sylvain Perruche   +6 more
doaj   +1 more source

Investigation of the prognostic value of CD4 T cell subsets expanded from tumor-infiltrating lymphocytes of colorectal cancer liver metastases

Journal for ImmunoTherapy of Cancer, 2020
Background The positive role of CD8+ tumor-infiltrating lymphocytes (TIL) in patients with colorectal cancer (CRC) has been well described but the prognostic value of CD4 T cell subsets remained to be investigated.
Olivier Adotevi, Marie Kroemer, Celia Turco, Laurie Spehner, Julien Viot, Idir Idirène, Adeline Bouard, Elodie Renaude, Marina Deschamps, Yann Godet, Samuel Limat, Bruno Heyd, Marine Jary, Romain Loyon, Christophe Borg   +14 more
doaj   +1 more source

The ATG8 Family Proteins GABARAP and GABARAPL1 Target Antigen to Dendritic Cells to Prime CD4⁺ and CD8⁺ T Cells

Cells, 2022
Vaccine therapy is a promising method of research to promote T cell immune response and to develop novel antitumor immunotherapy protocols. Accumulating evidence has shown that autophagy is involved in antigen processing and presentation to T cells.
Leïla Fonderflick, Timothée Baudu, Olivier Adotévi, Michaël Guittaut, Pascale Adami, Régis Delage-Mourroux   +5 more
doaj   +1 more source

PD-L1 expression is regulated by both DNA methylation and NF-kB during EMT signaling in non-small cell lung carcinoma

OncoImmunology, 2018
Tumor cells, which undergo Epithelial-mesenchymal transition (EMT) acquire increased capacities of proliferation, invasion and have the ability to generate metastases by escaping the immune system during their systemic migration.
A. Asgarova, K. Asgarov, Y. Godet, P. Peixoto, A. Nadaradjane, M. Boyer-Guittaut, J. Galaine, D. Guenat, V. Mougey, J. Perrard, J. R. Pallandre, A. Bouard, J. Balland, C. Tirole, O. Adotevi, E. Hendrick, M. Herfs, P. F. Cartron, C. Borg, E. Hervouet   +19 more
doaj   +1 more source

BPDCN: When polychemotherapy does not compromise allogeneic CD123 CAR‐T cell cytotoxicity

eJHaem, 2021
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy with poor prognosis and no treatment consensus. Combining chemotherapy and immunotherapy is a promising strategy to enhance therapeutic effect. Before combining these
Margaux Poussard, Laure Philippe, Maxime Fredon, Elodie Bôle‐Richard, Sabeha Biichle, Florian Renosi, Sophie Perrin, Marie Kroemer, Samuel Limat, Francis Bonnefoy, Etienne Daguindau, Eric Deconinck, Bérengère Gruson, Philippe Saas, Olivier Adotévi, Francine Garnache‐Ottou, Fanny Angelot‐Delettre   +16 more
doaj   +1 more source

Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite

Scientific Reports, 2017
While most subunit malaria vaccines provide only limited efficacy, pre-erythrocytic and erythrocytic genetically attenuated parasites (GAP) have been shown to confer complete sterilizing immunity.
Claudia Demarta-Gatsi, Roger Peronet, Leanna Smith, Sabine Thiberge, Robert Ménard, Salaheddine Mécheri   +5 more
doaj   +1 more source

Biology, ecology and dynamics of Deborrea malgassa (Heylarts 1884) (Lepidoptera: Psychidae), the main threat to apple Malus domestica Borkh growing in Madagascar

Agricultural and Forest Entomology, EarlyView.
Bioecology parameters of the endemic Psychidae Deborrea malgassa, the main pest of apple trees in Madagascar. Spatiotemporal dynamics of Deborrea malgassa, with a peak infestation between May and August. Proposed targeted prophylaxis techniques associated with other agroecological principles will be key to reducing the vulnerability of apple orchards ...
Miora Ranaivozandriny, Henriette Rasolofoarivao, Santatra Ravelomanantsoa, Bruno Rasmussen, Bertrand Muller, Lala Harivelo Raveloson Ravaomanarivo, Hélène Delatte   +6 more
wiley   +1 more source

“The Smell Makes Us Hungry”: When Food Is Not Medicine in Highland Madagascar

Culture, Agriculture, Food and Environment, EarlyView.
ABSTRACT In the wake of major disruptions to global supply chains during the Covid‐19 pandemic, the island nation of Madagascar pursued initiatives for auto‐suffisance, self‐sufficiency, in food supplies and medical treatments. Farming communities in the central highlands experienced an injunction to expand cultivation of both subsistence crops and ...
Gabrielle Robbins
wiley   +1 more source