Results 61 to 70 of about 5,328,680 (285)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Embeddings of anisotropic Sobolev spaces into spaces of anisotropic Hölder-continuous functions
Demonstratio MathematicaWe introduce a novel framework for embedding anisotropic variable exponent Sobolev spaces into spaces of anisotropic variable exponent Hölder-continuous functions within rectangular domains.
Eddine Nabil Chems, Repovš Dušan D.
doaj +1 more source
ε-Coverings of Hölder-Zygmund Type Spaces on Data-Defined Manifolds
Abstract and Applied Analysis, 2014 We first determine the asymptotes of the ε-covering numbers of Hölder-Zygmund type spaces on data-defined manifolds. Secondly, a fully discrete and finite algorithmic scheme is developed providing explicit ε-coverings whose cardinality is asymptotically ...
Martin Ehler, Frank Filbir
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Regularity Results for Hybrid Proportional Operators on Hölder Spaces
Fractal and FractionalRecently, a new type of derivative has been introduced, known as Caputo proportional derivatives. These are motivated by the applications of such derivatives (which are a generalization of Caputo’s standard fractional derivative) and the need to ...
Mieczysław Cichoń +2 more
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Kolmogorov inequalities for norms of Marchaud-type fractional derivatives of multivariate functions
Researches in Mathematics, 2020 We obtain new sharp Kolmogorov type inequalities, estimating the norm of mixed Marchaud type derivative of multivariate function through the C-norm of function itself and its norms in Hölder spaces.
N.V. Parfinovych, V.V. Pylypenko
doaj +1 more source
Calderón Operator on Local Morrey Spaces with Variable Exponents
Mathematics, 2021 In this paper, we establish the boundedness of the Calderón operator on local Morrey spaces with variable exponents. We obtain our result by extending the extrapolation theory of Rubio de Francia to the local Morrey spaces with variable exponents.
Kwok-Pun Ho
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A tightness criterion for random fields, with application to the Ising model
, 2017 We present a criterion for a family of random distributions to be tight in local H\"older and Besov spaces of possibly negative regularity. We then apply this criterion to the magnetization field of the two-dimensional Ising model at criticality ...
Furlan, Marco, Mourrat, Jean-Christophe
core +3 more sources
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source