Results 41 to 50 of about 342,789 (291)

Performance of a deep excavation and the influence on adjacent piles: A case history in karst region covered by clay and sand

open access: yesUnderground Space, 2023
This paper presents a case study of deep excavation adjacent to an existing bridge in karst region of Guangzhou city, China. The movements of retaining structures, settlements of surrounding ground and pipelines, and the responses of bridge piles were ...
Yubing Yang   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Design and Hardware Implementation Considerations of Modified Multilevel Cascaded H-Bridge Inverter for Photovoltaic System

open access: yesIEEE Access, 2019
Inverters are an essential part in many applications including photovoltaic generation. With the increasing penetration of renewable energy sources, the drive for efficient inverters is gaining more and more momentum. In this paper, output power quality,
Shuvangkar Shuvo   +5 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Overvoltage Crowbar Protection Based on Passive Power Supplied Control Unit

open access: yesPower Electronics and Drives
The increase in the involvement of renewable energy sources results in a high rate of semiconductor power converter applications. The power converters provide interconnections of DC microgrids with AC distribution lines.
Strossa Jan   +5 more
doaj   +1 more source

From potential to practice: how accelerating access to HPV tests and screen and treat programmes can help eliminate cervical cancer

open access: yesFamily Medicine and Community Health, 2019
Human papillomavirus (HPV) vaccination campaigns to prevent cervical cancer are being considered and implemented in countries around the world. While vaccination will protect future generations, it will not help the millions of women currently infected ...
William Cherniak   +8 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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