Results 61 to 70 of about 9,474,558 (312)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

DC-link voltage balancing in cascaded H-Bridge converters

Archives of Electrical Engineering, 2014
In this paper a DC-link voltage balancing strategy for multilevel Cascaded H-Bridge (CHB) converter is proposed. Presented solution bases on optimal choice of active vector durations in Space-Vector Pulse Width Modulation (SV-PWM).
Lewicki Arkadiusz
doaj   +1 more source

A Comparison of Nine Level Cascaded H-Bridge Multilevel Inverter with Five Level Cascaded H Bridge Multilevel Inverter

, 2023
The multilevel inverter utilization has been increased since the last decade. These new types of inverters are suitable in various high voltage & high-power application due to their ability to synthesize waveforms with better harmonic spectrum and faithful output. This paper presents a comparison of nine-level cascaded H-bridge multilevel inverter with
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Simple Analysis of the Second (Extra) Disulfide Bridge of V_HHs

Molecules
Camelids produce a special type of antibody, known as VHHs, that has lost the VL domain, providing a more optimised VH domain. This particular highly stable antibody domain has interesting properties for biotechnological development.
Carla Martins, Fabrice Gardebien, Aravindan Arun Nadaradjane, Julien Diharce, Alexandre G. de Brevern   +4 more
doaj   +1 more source

Monitoring Bridge Dynamic Behaviour Using an Instrumented Two Axle Vehicle

, 2012
Bridge & Infrastructure Research in Ireland 2010 (BRI 10), Cork, 2-3 September 2010Highway structures such as bridges are subject to continuous degradation primarily due to ageing, loading and environmental factors.
McGetrick, P., O\u27Brien, Eugene J., O'Brien, Eugene J., González, Arturo   +3 more
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Compensation techniques for non-linearities in H-bridge inverters

Journal of Electrical Systems and Information Technology, 2016
This paper presents compensation techniques for component non-linearities in H-bridge inverters as those used in grid-connected photovoltaic (PV) inverters.
Daniel Zammit, Cyril Spiteri Staines, Maurice Apap   +2 more
doaj   +1 more source

Natural Resource Inventory: Old Bridge Township, Middlesex County, New Jersey

, 1992
This updated natural resource inventory contains new soils data published by the Soil Conservation Service, a survey of plants and animals found in the Old Bridge Township, a listing of new environmental regulations, and a listing of unique natural ...

core   +1 more source