Results 61 to 70 of about 12,744,689 (299)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Managing quality improvement [PDF]

open access: yes, 1984
"November 1984."Bibliography: p. 49-50.Charles H.

core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Artificial Neural Network for Vertical Displacement Prediction of a Bridge from Strains (Part 1): Girder Bridge under Moving Vehicles

open access: yesApplied Sciences, 2019
A real-time prediction method using a multilayer feedforward neural network is proposed for estimating vertical dynamic displacements of a bridge from the longitudinal strains of the bridge when vehicles pass across it.
Hyun Su Moon   +3 more
doaj   +1 more source

Research on the Multilevel STATCOM based on the H-bridge Cascaded

open access: yesJournal of Networks, 2014
This paper mainly studies the main circuit topology, the working principle, modulation technique and control strategy of the STATCOM based on H-bridge. The STATCOM direct power control algorithm based on the virtual flux is used to control the AC side reactive power compensation, and in accordance with the principle of conservation of power, the DC ...
Guifeng Wang   +3 more
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Compensation techniques for non-linearities in H-bridge inverters

open access: yesJournal of Electrical Systems and Information Technology, 2016
This paper presents compensation techniques for component non-linearities in H-bridge inverters as those used in grid-connected photovoltaic (PV) inverters.
Daniel Zammit   +2 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

A Simple Analysis of the Second (Extra) Disulfide Bridge of VHHs

open access: yesMolecules
Camelids produce a special type of antibody, known as VHHs, that has lost the VL domain, providing a more optimised VH domain. This particular highly stable antibody domain has interesting properties for biotechnological development.
Carla Martins   +4 more
doaj   +1 more source

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