Results 41 to 50 of about 12,133,437 (297)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Design and Hardware Implementation Considerations of Modified Multilevel Cascaded H-Bridge Inverter for Photovoltaic System

IEEE Access, 2019
Inverters are an essential part in many applications including photovoltaic generation. With the increasing penetration of renewable energy sources, the drive for efficient inverters is gaining more and more momentum. In this paper, output power quality,
Shuvangkar Shuvo, Eklas Hossain, Tanveerul Islam, Abir Akib, Sanjeevikumar Padmanaban, Md. Ziaur Rahman Khan   +5 more
doaj   +1 more source

Protection scheme for LVDC distribution network based on stepwise blocking of power electronic transformer

IET Renewable Power Generation, 2023
Cascaded H‐bridge power electronic transformers (CHB‐PET) can efficiently connect AC/DC distribution networks, realizing power transmission and electric energy conversion.
Yongfan Guo, Tao Zheng, Wenxuan Lv, Yifan Li   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Overvoltage Crowbar Protection Based on Passive Power Supplied Control Unit

Power Electronics and Drives
The increase in the involvement of renewable energy sources results in a high rate of semiconductor power converter applications. The power converters provide interconnections of DC microgrids with AC distribution lines.
Strossa Jan, Damec Vladislav, Sobek Martin, Cyprich Pavel, Cyprich Petr, Kubatko Marek   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Active power decoupling and controlling for single-phase FACTS device

The Journal of Engineering, 2019
Single-phase FACTS device has a bulky and short-life electrolytic capacitor to absorb the ripple pulsating at twice of the line frequency in DC side, resulting in lower power density. This paper introduced a structure of three-phase bridge which added an
Junmin Zhang, Kaipei Liu, Yan Liu, Shunfan He, Wei Tian   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Individual Wellbeing and Bridge: An Empirical Analysis [PDF]

, 2017
There is a growing interest in the Sociology of bridge. This research is part of a wider examination of bridge from a sociological and medical perspective, and is conducted with the intention of providing some of the groundwork for a larger study of the ...
McDonnell, Diarmuid, Small, Caroline, Punch, Samantha   +2 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source