Results 51 to 60 of about 9,474,558 (312)

The Effect of Lane Changing on Long-Span Highway Bridge Traffic Loading

open access: yes, 2012
Bridge Maintenance, Safety, Management, Resilience & Sustainability, Sixth International IABMAS Conference, Stresa, Lake Maggiore, Italy, 8-12 July 2012Maximum loading on long-span bridges typically occurs in congested traffic conditions.
Carey, Colm   +8 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A NOVEL CASCADED H- BRIDGE MULTILEVEL INVERTER BASED ON OPTIMAL PWM TECHNIQUE

open access: yesElectrica, 2013
In this paper, a novel cascaded H- bridge multilevel inverter has been proposed using less number of switches. A standard cascaded multilevel inverter requires 4h number of switches for (2h + 1) levels whereas h is the number of dc sources. This proposed
A. MAHESWARI, I. GNANAMBAL
doaj   +2 more sources

Artificial Neural Network for Vertical Displacement Prediction of a Bridge from Strains (Part 1): Girder Bridge under Moving Vehicles

open access: yesApplied Sciences, 2019
A real-time prediction method using a multilayer feedforward neural network is proposed for estimating vertical dynamic displacements of a bridge from the longitudinal strains of the bridge when vehicles pass across it.
Hyun Su Moon   +3 more
doaj   +1 more source

Model Predictive Control of Multilevel Cascaded H-Bridge Inverters

open access: yesIEEE Transactions on Industrial Electronics, 2010
This paper presents a model predictive current control algorithm that is suitable for multilevel converters and its application to a three-phase cascaded H-bridge inverter. This control method uses a discrete-time model of the system to predict the future value of the current for all voltage vectors, and selects the vector which minimizes a cost ...
Patricio Cortes   +4 more
openaire   +3 more sources

Individual Wellbeing and Bridge: An Empirical Analysis [PDF]

open access: yes, 2017
There is a growing interest in the Sociology of bridge. This research is part of a wider examination of bridge from a sociological and medical perspective, and is conducted with the intention of providing some of the groundwork for a larger study of the ...
McDonnell, Diarmuid   +2 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

105 years with the interstate bridge

open access: yes, 2022
The Interstate Bridge opened on February 14, 1917 amid much fanfare. It cost travelers -- both vehicles and horses! -- five cents to cross the bridge. There were two lanes of traffic, one in each direction, as well as a streetcar.

core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

From potential to practice: how accelerating access to HPV tests and screen and treat programmes can help eliminate cervical cancer

open access: yesFamily Medicine and Community Health, 2019
Human papillomavirus (HPV) vaccination campaigns to prevent cervical cancer are being considered and implemented in countries around the world. While vaccination will protect future generations, it will not help the millions of women currently infected ...
William Cherniak   +8 more
doaj   +1 more source

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