Results 51 to 60 of about 25,699,961 (309)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The Gopakumar-Vafa formula for symplectic manifolds [PDF]

, 2013
The Gopakumar-Vafa conjecture predicts that the Gromov-Witten invariants of a Calabi-Yau 3-fold can be canonically expressed in terms of integer invariants called BPS numbers.
Eleny-Nicoleta Ionel, Thomas H. Parker
semanticscholar   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

On formality of homogeneous Sasakian manifolds

Complex Manifolds, 2019
In this note we show families of homogeneous Sasakian manifolds G/H which are nonformal. The non-formality condition is expressed in terms of characters of a maximal torus in G.
Morocka-Tralle Irena, Tralle Aleksy
doaj   +1 more source

Almost Kenmotsu 3-h-metric as a cotton soliton [PDF]

Arab Journal of Mathematical Sciences
Purpose – Cotton soliton is a newly introduced notion in the field of Riemannian manifolds. The object of this article is to study the properties of this soliton on certain contact metric manifolds.
Dibakar Dey, Pradip Majhi
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The minimal entropy problem for 3-manifolds with zero simplicial volume [PDF]

, 2003
In this note, we consider the minimal entropy problem, namely the question of whether there exists a smooth metric of minimal (topological) entropy, for certain classes of closed 3 ...
Anderson, J.W., Paternain, G.P.
core   +1 more source

Curvature Invariants of Statistical Submanifolds in Kenmotsu Statistical Manifolds of Constant ϕ-Sectional Curvature

Entropy, 2018
In this article, we consider statistical submanifolds of Kenmotsu statistical manifolds of constant ϕ-sectional curvature. For such submanifold, we investigate curvature properties. We establish some inequalities involving the normalized δ-Casorati
Simona Decu, Stefan Haesen, Leopold Verstraelen, Gabriel-Eduard Vîlcu   +3 more
doaj   +1 more source

Higher-derivative couplings and torsional Riemann curvature

Journal of High Energy Physics, 2022
Using the most general higher-derivative field redefinitions for the closed spacetime manifolds, we show that the tree-level couplings of the metric, B-field and dilaton at orders α′2 and α′3 that have been recently found by the T-duality, can be written
Mohammad R. Garousi
doaj   +1 more source

Complex manifolds with maximal torus actions [PDF]

Journal für die Reine und Angewandte Mathematik, 2013
In this paper, we introduce the notion of maximal actions of compact tori on smooth manifolds and study compact connected complex manifolds equipped with maximal actions of compact tori.
Hiroaki Ishida
semanticscholar   +1 more source