Results 71 to 80 of about 7,321 (260)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Quantum Lie systems and integrability conditions
, 2009 The theory of Lie systems has recently been applied to Quantum Mechanics and additionally some integrability conditions for Lie systems of differential equations have also recently been analysed from a geometric perspective.
Cariñena J. F. +7 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Group manifolds and homogeneous spaces with HKT geometry: The role of automorphisms
Nuclear Physics B, 2020 We present a new simple proof of the fact that certain group manifolds as well as certain homogeneous spaces G/H of dimension 4n admit a triple of integrable complex structures that satisfy the quaternionic algebra and are covariantly constant with ...
A.V. Smilga
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A survey of homotopy nilpotency and co-nilpotency
Pracì Mìžnarodnogo Geometričnogo Centru, 2020 We review known and state some new results on homotopy nilpotency and co-nilpotency of spaces. Next, we take up the systematic study of homotopy nilpotency of homogenous spaces G/K for a Lie group G and its closed subgroup K < G.
Marek Golasinski
doaj +1 more source
HyperK\"ahler Potentials via Finite-Dimensional Quotients
, 2000 It is known that nilpotent orbits in a complex simple Lie algebra admit hyperK\"ahler metrics with a single function that is a global potential for each of the K\"ahler structures (a hyperK\"ahler potential).
Kobak, Piotr, Swann, Andrew
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Hyper-ParaHermitian manifolds with torsion
, 2005 Necessary and sufficient conditions for the existence of a hyper-parahermitian connection with totally skew-symmetric torsion (HPKT-structure) are presented. It is shown that any HPKT-structure is locally generated by a real (potential) function.
Akivis +29 more
core +1 more source