Results 71 to 80 of about 25,699,961 (309)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Minimal Retraction of Space-time and Their Foldings [PDF]

, 2009
The folding of a manifold was, firstly introduced by Robertson in [1977] . Since then many authers have studied the folding of manifolds s. The deformation retracts of the manifolds defined and discussed.
El-Ahmady, A. E., Rafat, H.
core   +1 more source

Flow field and noise characteristics of manifold in natural gas transportation station

Oil & Gas Science and Technology, 2019
Manifolds play a role of pressure balance, buffering and rectification for different branch pipelines, the flow noise of manifolds has been a serious problem all this time in natural gas transmission station.
Su Zhongya, Liu Enbin, Xu Yawen, Xie Ping, Shang Chen, Zhu Qiyong   +5 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Kahler manifolds and their relatives [PDF]

, 2010
Let M1 and M2 be two K¨ahler manifolds. We call M1 and M2 relatives if they share a non-trivial K¨ahler submanifold S, namely, if there exist two holomorphic and isometric immersions (K¨ahler immersions) h1 : S → M1 and h2 : S → M2. Moreover, two K¨ahler
Loi, A., Di Scala, Antonio Jose'
core  

Subgroup separability, knot groups, and graph manifolds

, 2001
This paper answers a question of Burns, Karrass and Solitar by giving examples of knot and link groups which are not subgroup-separable. For instance, it is shown that the fundamental group of the square knot complement is not subgroup separable.
Wise, Daniel T., Niblo, Graham A.
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Almost Kenmotsu Manifolds

, 2023
The object of this paper is to study generalized φ-recurrent almost Kenmotsu manifolds with characteristic vector field ξ belonging to (k, µ)-nullity distribution.
Manjulamma, Uppara, H Nagaraja, Nagaraja, H,, Uppara Manjulamma, Nagaraja, H, G   +4 more
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Introduction to Symplectic Field Theory [PDF]

, 2000
We sketch in this article a new theory, which we call Symplectic Field Theory or SFT, which provides an approach to Gromov-Witten invariants of symplectic manifolds and their Lagrangian submanifolds in the spirit of topological field theory, and at the ...
Y. Eliashberg, A. Givental, H. Hofer
semanticscholar   +1 more source