Results 71 to 80 of about 23,363,338 (328)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Using Structured UKR Manifolds for Motion Classification and Segmentation

, 2009
Steffen JF, Pardowitz M, Ritter H. Using Structured UKR Manifolds for Motion Classification and Segmentation. In: Intelligent Robots and Systems (IROS).
Michael Pardowitz, Ritter, Helge ; https://orcid.org/, Jan Steffen, Pardowitz, Michael, Helge Ritter, Steffen, Jan Frederik   +5 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Almost Kenmotsu Manifolds

, 2023
The object of this paper is to study generalized φ-recurrent almost Kenmotsu manifolds with characteristic vector field ξ belonging to (k, µ)-nullity distribution.
Manjulamma, Uppara, H Nagaraja, Nagaraja, H,, Uppara Manjulamma, Nagaraja, H, G   +4 more
core   +1 more source

Flow field and noise characteristics of manifold in natural gas transportation station

Oil & Gas Science and Technology, 2019
Manifolds play a role of pressure balance, buffering and rectification for different branch pipelines, the flow noise of manifolds has been a serious problem all this time in natural gas transmission station.
Su Zhongya, Liu Enbin, Xu Yawen, Xie Ping, Shang Chen, Zhu Qiyong   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Introduction to Symplectic Field Theory [PDF]

, 2000
We sketch in this article a new theory, which we call Symplectic Field Theory or SFT, which provides an approach to Gromov-Witten invariants of symplectic manifolds and their Lagrangian submanifolds in the spirit of topological field theory, and at the ...
Y. Eliashberg, A. Givental, H. Hofer
semanticscholar   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Beurling-Landau's density on compact manifolds

, 2012
Given a compact Riemannian manifold $M$, we consider the subspace of $L^2(M)$ generated by the eigenfunctions of the Laplacian of eigenvalue less than $L\geq1$.
Ortega-Cerdà, Joaquim, Ortega Cerdà, Joaquim, Pridhnani, Bharti   +2 more
core   +1 more source

Almost formality of manifolds of low dimension [PDF]

, 2021
In this paper we introduce the notion of Poincaré DGCAs of Hodge type, which is a subclass of Poincaré DGCAs encompassing the de Rham algebras of closed orientable manifolds.
Van Le H., Kawai K., Fiorenza D., Schwachhofer L.   +3 more
core   +1 more source