Results 81 to 90 of about 7,321 (260)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Design and Practical Stability of a New Class of Impulsive Fractional-Like Neural Networks
Entropy, 2020 In this paper, a new class of impulsive neural networks with fractional-like derivatives is defined, and the practical stability properties of the solutions are investigated. The stability analysis exploits a new type of Lyapunov-like functions and their
Gani Stamov +3 more
doaj +1 more source
Symmetric Spaces in Supergravity
, 2008 We exploit the relation among irreducible Riemannian globally symmetric spaces (IRGS) and supergravity theories in 3, 4 and 5 space-time dimensions.
Ferrara, S., Marrani, A.
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Variational inequality problems in H-spaces
International Journal of Mathematics and Mathematical Sciences, 2006 The concept of η-invex set is explored and the concept of T-η-invex function is introduced. These concepts are applied to the generalized vector variational inequality problems in ordered topological vector spaces.
Akrur Behera, Prasanta Kumar Das
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Yang-Mills fields in flux compactifications on homogeneous manifolds with SU(4)-structure
, 2012 The SU(4)-instanton equations are natural BPS equations for instantons on 8-manifolds. We study these equations on nearly Kaehler and Calabi-Yau torsion manifolds of the form M x G/H, with G/H a coset space and M a product of a torus with Euclidean space.
Harland, Derek, Popov, Alexander D.
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Brieskorn manifolds as contact branched covers of spheres
, 2005 We show that Brieskorn manifolds with their standard contact structures are contact branched coverings of spheres. This covering maps a contact open book decomposition of the Brieskorn manifold onto a Milnor open book of the sphere.Comment: 8 pages, 1 ...
C. Caubel +11 more
core +1 more source