Results 101 to 110 of about 7,321 (260)

The LLV Algebra for Primitive Symplectic Varieties with Isolated Singularities [PDF]

Épijournal de Géométrie Algébrique
We extend results of Looijenga--Lunts and Verbitsky and show that the total Lie algebra $\mathfrak g$ for the intersection cohomology of a primitive symplectic variety $X$ with isolated singularities is isomorphic to $$\mathfrak g \cong \mathfrak{so ...
Benjamin Tighe
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

The topology of Double Field Theory

Journal of High Energy Physics, 2018
We describe the doubled space of Double Field Theory as a group manifold G with an arbitrary generalized metric. Local information from the latter is not relevant to our discussion and so G only captures the topology of the doubled space.
Falk Hassler
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Manifestly T-dual formulation of AdS space

Journal of High Energy Physics, 2017
We present a manifestly T-dual formulation of curved spaces such as an AdS space. For group manifolds related by the orthogonal vielbein fields the three form H = dB in the doubled space is universal at least locally. We construct an affine nondegenerate
Machiko Hatsuda, Kiyoshi Kamimura, Warren Siegel   +2 more
doaj   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Maximally supersymmetric AdS solutions and their moduli spaces

Journal of High Energy Physics, 2018
We study maximally supersymmetric AdS D solutions of gauged supergravities in dimensions D ≥ 4. We show that such solutions can only exist if the gauge group after spontaneous symmetry breaking is a product of two reductive groups H R × H mat, where H R ...
Severin Lüst, Philipp Rüter, Jan Louis
doaj   +1 more source

A General Type of Almost Contact Manifolds [PDF]

Among almost contact manifolds Sasakian manifolds, Kenmotsu manifolds (called also “a certain class of almost contact manifolds”) and cosymplectic manifolds have been studied by many authors.
Catalin Angelo Ioan
core   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source