Results 101 to 110 of about 139,667 (256)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba   +25 more
wiley   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

open access: yesAdvanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen   +10 more
wiley   +1 more source

Flexor carpi radialis H-reflex in different body positions in patients with post-stroke. [PDF]

open access: yesFront Neurol, 2022
Ma JY   +5 more
europepmc   +1 more source

Lightweight, Elastic Ceramic Fabrics for Broadband Electromagnetic Absorption and High Temperature Thermal Insulation

open access: yesAdvanced Science, EarlyView.
This study reports lightweight, elastic ceramic fabrics with broadband electromagnetic absorption (EAB = 9.8 GHz) and high‐temperature thermal insulation, enabled by precise microstructural control during ultrafast high‐temperature sintering (UHS), which induces the precipitation of defect‐rich t‐ZrO2 nanograins and turbostratic C nanoclusters.
Jiahao Yang   +9 more
wiley   +1 more source

Corticospinal modulation of vibration-induced H-reflex depression. [PDF]

open access: yesExp Brain Res, 2022
Bringman CL, Shields RK, DeJong SL.
europepmc   +1 more source

Non‐Line‐of‐Sight Passive Ammonia Sensor Loaded With MXene/In2O3 Composites for Agricultural Products Quality Deterioration Detection

open access: yesAdvanced Science, EarlyView.
This study presents a flexible, battery‐free passive RFID sensing platform for NLoS monitoring of quality deterioration in fresh agricultural products. It utilizes a structurally decoupled spiral antenna‐LC electrode architecture to suppress electromagnetic interference caused by packaging.
Guoping Hu   +4 more
wiley   +1 more source

Effects of voluntary contraction on the soleus H-reflex of different amplitudes in healthy young adults and in the elderly. [PDF]

open access: yesFront Hum Neurosci, 2022
Batista-Ferreira L   +5 more
europepmc   +1 more source

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