Results 111 to 120 of about 141,787 (254)

Effects of voluntary contraction on the soleus H-reflex of different amplitudes in healthy young adults and in the elderly. [PDF]

Front Hum Neurosci, 2022
Batista-Ferreira L, Rabelo NF, da Cruz GM, Costa JNA, Elias LA, Mezzarane RA.   +5 more
europepmc   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Effects of Dry Needling on Spasticity in Multiple Sclerosis Evaluated Through the Rate-Dependent Depression of the H Reflex: A Case Report. [PDF]

Int Med Case Rep J, 2023
León F, Manzo L, Kababie R, Figueroa J, Cuellar C, Herrero P.   +5 more
europepmc   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

The Gray Zone of H-Reflex in Runners: When Should We Suspect Pathology? A Pilot Study. [PDF]

J Clin Med
De Silva LHMP, Maznychenko A, Gorkovenko A, Kolosova O, Abramovych T, Vlasenko OV, Melenko V, Sulyma O, Poruchynska T, Sokolowska I.   +9 more
europepmc   +1 more source

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source

Divergent Effects of Calcium Channel Modulators on H-Reflex Excitability in Fatigued Rat Muscle. [PDF]

Int J Mol Sci
Maznychenko A, Abramovych TI, Bulgakova NV, Melenko V, Levchuk YA, Shevchuk T, Sokolowska I, Kostyukov AI.   +7 more
europepmc   +1 more source

Biomarkers for rapid H-reflex operant conditioning among females.

J Neurophysiol, 2023
Johnson KA, Petrie MA, Shields RK.
europepmc   +1 more source

Spinal cord H-reflex post-activation depression is linked with hand motor control in adults with cerebral palsy. [PDF]

Clin Neurophysiol, 2023
Dukkipati SS, Walker SJ, Trevarrow MP, Busboom MT, Kurz MJ.   +4 more
europepmc   +1 more source