Robust shape optimization method for a linear elastic structure with unknown loadings
In this paper, we propose a robust shape optimization method for a linear elastic structure with unknown loadings. The concept of principal compliance for minimizing the maximal compliance in the unknown loadings is applied to a shape optimization ...
Masatoshi SHIMODA +3 more
doaj +1 more source
A New Mixed Element Method for a Class of Time-Fractional Partial Differential Equations
A kind of new mixed element method for time-fractional partial differential equations is studied. The Caputo-fractional derivative of time direction is approximated by two-step difference method and the spatial direction is discretized by a new mixed ...
Yang Liu +4 more
doaj +1 more source
Free-form optimization method of frame structures for elastic buckling
In this study, we propose a shape optimization method of a frame structure for maximizing the elastic buckling load. The 1st buckling load factor is maximized under a volume constraint.
Masatoshi SHIMODA, Ryo YOSHIMOTO
doaj +1 more source
Shape optimization of viscous flow domain considering unsteady fluid structure interaction
This paper presents numerical solution to shape design problems of viscous flow field for unsteady fluid-structure-interactive (FSI) fields. In the FSI analysis, a strong coupled analysis is used to analyze the governing equation of the flow domain and ...
Eiji KATAMINE, Seiya SHIMAKAWA
doaj +1 more source
Error analysis of the H1 gradient method for shape-optimization problems of continua [PDF]
We present an error estimation for the H1 gradient method, which provides numerical solutions to the shape-optimization problem of the domain in which a boundary value problem is defined.
Azegami, Hideyuki, Murai, Daisuke
core +1 more source
A method for improving the performance of gradient systems for diffusion-weighted MRI [PDF]
The MR signal is sensitive to diffusion. This effect can be increased by the use of large, balanced bipolar gradients. The gradient systems of MR scanners are calibrated at installation and during regular servicing visits.
Daniel C. Alex +11 more
core +1 more source
The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription [PDF]
Epithelial tight junctions recruit different types of signalling proteins that regulate cell proliferation and differentiation. Little is known about how such proteins interact functionally and biochemically with each other.
Leefa Chong San, I.V. +9 more
core +1 more source
Moving force identification based on modified preconditioned conjugate gradient method [PDF]
This paper develops a modified preconditioned conjugate gradient (M-PCG) method for moving force identification (MFI) by improving the conjugate gradient (CG) and preconditioned conjugate gradient (PCG) methods with a modified Gram-Schmidt algorithm. The
Zhen Chen +5 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

