Results 51 to 60 of about 11,657,814 (247)

A Coupling Method of New EMFE and FE for Fourth-Order Partial Differential Equation of Parabolic Type

open access: yesAdvances in Mathematical Physics, 2013
We propose and analyze a new numerical method, called a coupling method based on a new expanded mixed finite element (EMFE) and finite element (FE), for fourth-order partial differential equation of parabolic type.
Yang Liu   +4 more
doaj   +1 more source

Optimization approach for designing free-orientation of orthotropic materials of a shell structure

open access: yesNihon Kikai Gakkai ronbunshu, 2017
In this study, we propose a parameter-free optimization method of material orientation for a shell structure consisting of orthotropic materials. We consider the compliance as an objective function and minimize it under the state equation constraint. The
Yoshiaki MURAMATSU, Masatoshi SHIMODA
doaj   +1 more source

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti   +10 more
wiley   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão   +5 more
wiley   +1 more source

Interface shape identification of three-dimensional thermo-elastic composite structures consisting of dissimilar materials

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Shape design of composite structures composed of dissimilar materials moves more into the field of vision for designers. In this paper we propose a shape identification method for the interface and/or outside shape design of composite structures ...
Masatoshi SHIMODA   +2 more
doaj   +1 more source

DEVELOPMENT AND VALIDATION OF METHODS FOR QUANTITATIVE DETERMINATION OF ACTIVE PHARMACEUTICAL SUBSTANCES IN NASAL SPRAY

open access: yesФармация и фармакология (Пятигорск), 2021
Intranasal administration of H1-histamine receptor blockers may be a promising approach to the treatment of allergic rhinitis. Earlier, an original composition of a nasal spray containing fexofenadine hydrochloride and ammonium glycyrrhizinate and ...
M. V. Larskiy   +3 more
doaj   +1 more source

Interfacial Failure and Self‐Healing in Solid‐State Batteries

open access: yesAdvanced Materials, EarlyView.
Dynamic interfacial self‐healing offers an adaptive route to mitigate coupled mechanical, chemical, and electrochemical degradation in solid‐state batteries. This review connects evolving interfacial failure mechanisms with physical‐flow, chemical‐restoration, stimuli‐responsive, and electric‐field‐assisted repair strategies, highlighting targeted self‐
Xinxin Zhu   +8 more
wiley   +1 more source

A new shape optimization with robustness and its application for brake squeal phenomena

open access: yesNihon Kikai Gakkai ronbunshu, 2016
This paper proposes a new shape optimization with robustness, and its application for disc brake squeal phenomena is shown. The disc brake squeal is known as self-excited vibration; the real and imaginary parts of the complex eigenvalue indicate the ...
Kohei FURUYA   +2 more
doaj   +1 more source

Recent Advances of Slip Sensors for Smart Robotics

open access: yesAdvanced Materials Technologies, EarlyView.
This review summarizes recent progress in robotic slip sensors across mechanical, electrical, thermal, optical, magnetic, and acoustic mechanisms, offering a comprehensive reference for the selection of slip sensors in robotic applications. In addition, current challenges and emerging trends are identified to advance the development of robust, adaptive,
Xingyu Zhang   +8 more
wiley   +1 more source

Establishment of the Cell Line that Human Lung Adenocarcinoma can Stably Express Luciferase Which is Absent of nm23-H1 Expression and Detecting Its Luminescence 
in vitro and in vivo

open access: yesChinese Journal of Lung Cancer, 2012
Background and objective On the condition that laboratory animals survive, we can detect the distribution of tumor cells by in vivo imaging that were labeled with firefly- luciferase (luc) gene.
Hongming WANG   +3 more
doaj   +1 more source

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