Results 61 to 70 of about 186,953 (245)

Error estimates for a semidiscrete finite element method for fractional order parabolic equations

, 2012
We consider the initial boundary value problem for the homogeneous time-fractional diffusion equation $\partial^\alpha_t u - \De u =0$ ($0< \alpha < 1$) with initial condition $u(x,0)=v(x)$ and a homogeneous Dirichlet boundary condition in a bounded ...
Jin, Bangti, Lazarov, Raytcho, Zhou, Zhi
core   +2 more sources

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Optimization approach for designing free-orientation of orthotropic materials of a shell structure

Nihon Kikai Gakkai ronbunshu, 2017
In this study, we propose a parameter-free optimization method of material orientation for a shell structure consisting of orthotropic materials. We consider the compliance as an objective function and minimize it under the state equation constraint. The
Yoshiaki MURAMATSU, Masatoshi SHIMODA
doaj   +1 more source

DEVELOPMENT AND VALIDATION OF METHODS FOR QUANTITATIVE DETERMINATION OF ACTIVE PHARMACEUTICAL SUBSTANCES IN NASAL SPRAY

Фармация и фармакология (Пятигорск), 2021
Intranasal administration of H1-histamine receptor blockers may be a promising approach to the treatment of allergic rhinitis. Earlier, an original composition of a nasal spray containing fexofenadine hydrochloride and ammonium glycyrrhizinate and ...
M. V. Larskiy, A. E. Pozdnyakova, Z. D. Khadzhieva, D. I. Pozdnyakov   +3 more
doaj   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

A new shape optimization with robustness and its application for brake squeal phenomena

Nihon Kikai Gakkai ronbunshu, 2016
This paper proposes a new shape optimization with robustness, and its application for disc brake squeal phenomena is shown. The disc brake squeal is known as self-excited vibration; the real and imaginary parts of the complex eigenvalue indicate the ...
Kohei FURUYA, Kohei SHINTANI, Satoshi ITO   +2 more
doaj   +1 more source

Learning Deep Structured Models [PDF]

, 2015
Many problems in real-world applications involve predicting several random variables which are statistically related. Markov random fields (MRFs) are a great mathematical tool to encode such relationships.
Chen, Liang-Chieh, Schwing, Alexander G., Urtasun, Raquel, Yuille, Alan L.   +3 more
core   +1 more source

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

Advanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal, Majd Bisharat, Bassma Khamaisi, Krishanu Ghosal, Eid Nassar‐Marjiya, Qi Wu, Shadi Daoud, Idan Redenski, Samer Srouji, Shady Farah   +9 more
wiley   +1 more source

Establishment of the Cell Line that Human Lung Adenocarcinoma can Stably Express Luciferase Which is Absent of nm23-H1 Expression and Detecting Its Luminescence 
in vitro and in vivo

Chinese Journal of Lung Cancer, 2012
Background and objective On the condition that laboratory animals survive, we can detect the distribution of tumor cells by in vivo imaging that were labeled with firefly- luciferase (luc) gene.
Hongming WANG, Daxing ZHU, Zhihao WU, Qinghua ZHOU   +3 more
doaj   +1 more source

Moth‐Wing‐Inspired Multifunctional Metamaterials

Advanced Materials, EarlyView.
This study develops a moth‐wing‐inspired heterogeneous metamaterial that achieves synergistic broadband sound absorption, mechanical energy dissipation, and thermal insulation within a lightweight architected framework. Combining bioinspired gradient design, genetic‐algorithm optimization, and additive manufacturing, the bionic heterogeneous acoustic ...
Haoran Pei, Hang Yang, Ning Zhang, Tian Li, Xinxin Wang, Miao Zhao, Shuwei Ding, Xin Wang, Qinniu Lv, Zijie Xu, Yinghong Chen, Xinwei Li, Wei Zhai   +12 more
wiley   +1 more source