Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation. [PDF]
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Zhang SS +7 more
europepmc +2 more sources
Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice. [PDF]
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Ruan B +9 more
europepmc +2 more sources
Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom [PDF]
An analysis was undertaken to measure age-specific vaccine effectiveness (VE) of 2010/11 trivalent seasonal influenza vaccine (TIV) and monovalent 2009 pandemic influenza vaccine (PIV) administered in 2009/2010.
Ellis, J. +15 more
core +4 more sources
Influenza A (H1N1) 2009 : impact on Frankfurt in due consideration of health care and public health [PDF]
Background: In April 2009 a novel influenza A H1N1/2009 virus was identified in Mexico and in the United States which quickly spread around the world.
Harald Bias +14 more
core +1 more source
Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza [PDF]
Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine Methods: We ...
Harald Bias +15 more
core +1 more source
Post-pandemic seroprevalence of pandemic influenza A (H1N1) 2009 infection (swine flu) among children <18 years in Germany. [PDF]
We determined antibodies to the pandemic influenza A (H1N1) 2009 virus in children to assess: the incidence of (H1N1) 2009 infections in the 2009/2010 season in Germany, the proportion of subclinical infections and to compare titers in vaccinated and ...
Thomas Mertens +65 more
core +2 more sources
Clinical Profile of Patients Admitted with Swine-Origin Influenza A (H1N1) Virus Infection: An Experience from A Tertiary Care Hospital [PDF]
Background: Pandemic influenza A (H1N1) 2009 has posed a serious public health challenge world-wide. H1N1 critical illness mostly affects young patients and is often fatal.
Asmita A. Mehta +5 more
doaj +1 more source
Estimation of outbreak severity and transmissibility : influenza A(H1N1)pdm09 in households [PDF]
When an outbreak of a novel pathogen occurs, some of the most pressing questions from a public-health point of view relate to its transmissibility, and the probabilities of different clinical outcomes following infection, to allow an informed response ...
Inglis, N. +38 more
core +2 more sources
Replication, Pathogenesis and Transmission of Pandemic (H1N1) 2009 Virus in Non-Immune Pigs [PDF]
The declaration of the human influenza A pandemic (H1N1) 2009 (H1N1/09) raised important questions, including origin and host range [1,2]. Two of the three pandemics in the last century resulted in the spread of virus to pigs (H1N1, 1918; H3N2, 1968 ...
Essen, Stephen C. +82 more
core +2 more sources
Rapport national de mi-saison sur l’influenza au Canada, 2019 à 2020
Au Canada, la saison nationale de la grippe a commencé à la semaine 47, entre le 17 et le 23 novembre 2019. Des 3 762 détections des cas de grippe confirmées en laboratoire ayant été signalées entre le 25 août et le 14 décembre 2019, 61 % étaient de type
Claire Sevenhuysen +7 more
doaj +1 more source

