Results 41 to 50 of about 88,273 (209)
Advanced Science, EarlyView.This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding +13 more
wiley +1 more source
Advanced Science, EarlyView.An intelligent odor monitoring system integrates an IVC animal model, gas sensor array, real‐time resistance readout, and machine‐learning analysis to continuously monitor infection‐associated odor changes. The platform captures longitudinal sensor responses, distinguishes infected from healthy states, and supports early‐stage respiratory viral ...
Yajie Shen +17 more
wiley +1 more source
Southern Clinics of Istanbul Eurasia, 2017 INTRODUCTION[|]The aim of the present study was to determine the etiological profile, clinical course, and outcome of patients hospitalized with severe influenza during the 2015-2016 influenza season.[¤]METHODS[|]Patients with severe influenza who were ...
Ayşe Batırel +6 more
doaj +1 more source
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
The practitioners guide for dealing with the novel Influenza A, H1n1 pandemic
South African Family Practice, 2009 Within three months of its discovery, the new Influenza A (H1n1) swineflu strain has spread to such an extent that a pandemic has been declared by the World Health Organization (WHO). Although most cases seem to be mild, cases of severe disease have also
Marietjie Venter, L. Bloomberg
doaj +1 more source
Advanced Science, EarlyView.A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan +9 more
wiley +1 more source
National Influenza Mid-Season Report, 2019–2020
Canada Communicable Disease Report, 2020 Canada’s national influenza season started in week 47 between November 17 to 23, 2019. Of the 3,762 laboratory-confirmed influenza detections reported from August 25 to December 14, 2019, 61% were influenza A, and of those subtyped, 68% were A(H3N2 ...
Claire Sevenhuysen +7 more
doaj +1 more source
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Acta Veterinaria, 2014 The 2009 outbreak of H1N1 influenza A viruses in humans underscored the importance of pigs in influenza A virus evolution and the emergence of novel viruses with pandemic potential.
Mašić Aleksandar +4 more
doaj +1 more source
Clinical Evaluation of Cases of Pandemic H1N1 Influenza in Sanliurfa Province in Epidemic Period
Acta Medica Alanya, 2018 Aim: In this study, we aimed to share our experience with 75 patients admitted to the hospital who adhered to the definition of influenza-like illness.Patients and Methods: Pandemic 2009 influenza positive and negative cases with RNA (ribonucleic acid ...
Halil Kazanasmaz +4 more
doaj +1 more source