Results 51 to 60 of about 122,925 (198)

Rapport national de mi-saison sur l’influenza au Canada, 2020–2021

Canada Communicable Disease Report, 2021
Au Canada, la saison nationale de la grippe commence généralement dans la seconde moitié du mois de novembre (semaine 47) et elle est définie comme la semaine où au moins 5 % des tests de grippe sont positifs et où un minimum de 15 tests positifs sont ...
Liza Lee, Kelly Butt, Steven Buckrell, Andrea Nwosu, Claire Sevenhuysen, Christina Bancej   +5 more
doaj   +1 more source

Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli

Advanced Science, EarlyView.
Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma, Yuxin Zhang, Lujia Sun, Hong Jiang, Fan Li, Wenming Liu, Shenao Zhou, Mengting Wang, Weijian Huang, Xu Zhou, Caiyang Chen, Qiuqiu Zhang, Xiaoyan Jin, Feihan Yan, Hongping Wu, Yonghong Yin, Xinling Wang, Hexin Yan, Weifeng Yu   +18 more
wiley   +1 more source

Integrated Microfluidic Preconcentration and Nucleic Amplification System for Detection of Influenza A Virus H1N1 in Saliva

Micromachines, 2020
Influenza A viruses are often present in environmental and clinical samples at concentrations below the limit of detection (LOD) of molecular diagnostics.
Yonghee Kim, Abdurhaman Teyib Abafogi, Buu Minh Tran, Jaewon Kim, Jinyeop Lee, Zhenzhong Chen, Pan Kee Bae, Kyoungsook Park, Yong-Beom Shin, Danny van Noort, Nae Yoon Lee, Sungsu Park   +11 more
doaj   +1 more source

NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication

Advanced Science, EarlyView.
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma, Changyuan Kang, Xixian Liu, Lichao Yang, Mengyi Li, Yuting Ye, Jianfang Zhang, Yingjun Li, Guanghui Jin, Yang Liu, Xiaohong Chen, Kexin Wang, Zifeng Yang   +12 more
wiley   +1 more source

Genomic and Clinical Analysis of Influenza A in Hospitalized Adults, 2019-2024: Exploratory Evidence on Neuraminidase and Polymerase Acidic Protein Mutation-Outcome Associations From a Single Center. [PDF]

Influenza Other Respir Viruses
ABSTRACT Background Antivirals are widely used to treat influenza, but potential resistance mutations remain a major challenge, and clinical data on key resistance mutations are limited. Methods We conducted a retrospective cohort study of 765 adults with RT‐PCR‐confirmed influenza A admitted to Ruijin Hospital, Shanghai, between 2019 and 2024 to ...
Feng A, Tan W, Xu W, Zhang X, Wei D, Yang Z.   +5 more
europepmc   +2 more sources

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Etiology and Clinical Course of Patients with Severe Influenza/Acute Respiratory Infection Requiring Hospitalization During the 2015-2016 Influenza Season

Southern Clinics of Istanbul Eurasia, 2017
INTRODUCTION[|]The aim of the present study was to determine the etiological profile, clinical course, and outcome of patients hospitalized with severe influenza during the 2015-2016 influenza season.[¤]METHODS[|]Patients with severe influenza who were ...
Ayşe Batırel, Semih Korkut, Recep Demirhan, Ayşe Karaaslan, Banu Eler Çevik, Sevda Şener Cömert, Engin Ersin Şimşek   +6 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

The Effect of Risk Perception on the 2009 H1N1 Pandemic Influenza Dynamics [PDF]

, 2011
Background: The 2009 H1N1 pandemic influenza dynamics in Italy was characterized by a notable pattern: as it emerged from the analysis of influenza-like illness data, after an initial period (September–mid-October 2009) characterized by a slow ...
Poletti Piero, Poletti, Piero, Ajelli, Marco, Merler Stefano, Stefano Merler, S. Merler, Merler, Stefano, Piero Poletti, Marco Ajelli, Ajelli Marco, M. Ajelli   +10 more
core   +1 more source

The practitioners guide for dealing with the novel Influenza A, H1n1 pandemic

South African Family Practice, 2009
Within three months of its discovery, the new Influenza A (H1n1) swineflu strain has spread to such an extent that a pandemic has been declared by the World Health Organization (WHO). Although most cases seem to be mild, cases of severe disease have also
Marietjie Venter, L. Bloomberg
doaj   +1 more source