Results 61 to 70 of about 178,155 (246)

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Etiology and Clinical Course of Patients with Severe Influenza/Acute Respiratory Infection Requiring Hospitalization During the 2015-2016 Influenza Season

Southern Clinics of Istanbul Eurasia, 2017
INTRODUCTION[|]The aim of the present study was to determine the etiological profile, clinical course, and outcome of patients hospitalized with severe influenza during the 2015-2016 influenza season.[¤]METHODS[|]Patients with severe influenza who were ...
Ayşe Batırel, Semih Korkut, Recep Demirhan, Ayşe Karaaslan, Banu Eler Çevik, Sevda Şener Cömert, Engin Ersin Şimşek   +6 more
doaj   +1 more source

The Iowa Perinatal Letter, July-August-September 2009, Vol. 30, no. 3 [PDF]

, 2009
This newsletter from The Department of Public Health about perinatal health care and ...

core  

Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus [PDF]

, 2014
The source, timing, and geographical origin of the 1918–1920 pandemic influenza A virus have remained tenaciously obscure for nearly a century, as have the reasons for its unusual severity among young adults.
A. Rambaut, Adalja, Antonovics, Davenport, Dowdle, Fan, FROST, G.-Z. Han, Kawaoka, KENDAL, M. Worobey, Masurel, Masurel, Masurel, Masurel, Molinari, Morens, Mulder, Nelson, REKART, SCHOENBAUM, Schulman, Shanks, Shanks, Taubenberger, Thompson, Thompson, Waffarn, Webster, Wolfe   +29 more
core   +2 more sources

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

The practitioners guide for dealing with the novel Influenza A, H1n1 pandemic

South African Family Practice, 2009
Within three months of its discovery, the new Influenza A (H1n1) swineflu strain has spread to such an extent that a pandemic has been declared by the World Health Organization (WHO). Although most cases seem to be mild, cases of severe disease have also
Marietjie Venter, L. Bloomberg
doaj   +1 more source

Integrating influenza antigenic dynamics with molecular evolution. [PDF]

, 2013
Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains ...
Abed, Ansaldi, Ansaldi, Barr, Barr, Bedford, Bedford, Bogner, Borodin, Cai, Centers for Disease Control and Prevention, Chakraverty, Chakraverty, Cox, Cox, Daniels, Daum, Daum, Donatelli, Drummond, Edgar, Ferguson, Fitch, Gog, Goldstein, Gust, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hensley, Hirst, Kanegae, Kendal, Klimov, Koel, Lemey, Li, Lin, Lin, Lin, Lin, Matsuzaki, McCauley, McCauley, McCauley, McCauley, McCauley, McDonald, Muyanga, Nakagawa, Nakajima, Nakajima, Nakajima, Nelson, Nerome, Oh, Osterholm, Pagel, Pereira, Puzelli, Pybus, Raymond, Rota, Russell, Shapiro, Shaw, Smith, Squires, Stevens, Webster, Wiley, World Health Organization, Xu   +83 more
core   +4 more sources

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source

National Influenza Mid-Season Report, 2019–2020

Canada Communicable Disease Report, 2020
Canada’s national influenza season started in week 47 between November 17 to 23, 2019. Of the 3,762 laboratory-confirmed influenza detections reported from August 25 to December 14, 2019, 61% were influenza A, and of those subtyped, 68% were A(H3N2 ...
Claire Sevenhuysen, Liza Lee, Andrea Nwosu, Tiffany Smith, Lindsay Whitmore, Nathalie Bastien, Mireille Desroches, Christina Bancej   +7 more
doaj   +1 more source

Expert-Led Securitization: The Case of the 2009 Pandemic in Denmark and Sweden

Politics and Governance, 2020
This article goes beyond the study of speech acts to investigate the process of securitization during a health crisis. The article introduces the concept of ‘expert-led securitization’ to account for situations when experts dominate the administrative ...
Olivier Rubin, Erik Baekkeskov
doaj   +1 more source