Results 81 to 90 of about 120,380 (259)

Capturing the time-varying drivers of an epidemic using stochastic dynamical systems. [PDF]

, 2013
Epidemics are often modeled using non-linear dynamical systems observed through partial and noisy data. In this paper, we consider stochastic extensions in order to capture unknown influences (changing behaviors, public interventions, seasonal effects ...
Baguelin, Marc, Dureau, Joseph, Kalogeropoulos, Konstantinos   +2 more
core   +1 more source

A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA

Acta Paediatrica, EarlyView.
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley   +1 more source

Host Modulators of H1N1 Cytopathogenicity

PLoS ONE, 2012
Influenza A virus infects 5-20% of the population annually, resulting in ~35,000 deaths and significant morbidity. Current treatments include vaccines and drugs that target viral proteins. However, both of these approaches have limitations, as vaccines require yearly development and the rapid evolution of viral proteins gives rise to drug resistance ...
Ward, Samuel E, Kim, Hyun Seok, Komurov, Kakajan, Mendiratta, Saurabh, Tsai, Pei-Ling, Schmolke, Mirco, Satterly, Neal, Manicassamy, Balaji, Forst, Christian V, Roth, Michael G, García-Sastre, Adolfo, Blazewska, Katarzyna M, McKenna, Charles E, Fontoura, Beatriz M, White, Michael A   +14 more
openaire   +5 more sources

Real-time characterization of the molecular epidemiology of an influenza pandemic [PDF]

, 2013
Early characterization of the epidemiology and evolution of a pandemic is essential for determining the most appropriate interventions. During the 2009 H1N1 influenza A pandemic, public databases facilitated widespread sharing of genetic sequence data ...
Lycett, Samantha J., Lycett, S. J., Hedge, J., Rambaut, A, Rambaut, Andrew, Rambaut, A., Hedge, Jessica, Lycett, S J; id_orcid   +7 more
core   +1 more source

Government support, regional well‐being, and the pivots of UK SMEs during a crisis

European Management Review, EarlyView.
Abstract Pivoting—a substantive transformation of the established business model (e.g., reformulation of goods, services, processes, or organizational methods in a new or significantly improved manner)—has emerged as a crisis response strategy of small‐ and medium‐sized enterprises (SMEs).
Chau M. Chu, Bach Nguyen
wiley   +1 more source

Comparison of CATs, CURB-65 and PMEWS as triage tools in pandemic influenza admissions to UK hospitals: case control analysis using retrospective data [PDF]

, 2012
Triage tools have an important role in pandemics to identify those most likely to benefit from higher levels of care. We compared Community Assessment Tools (CATs), the CURB-65 score, and the Pandemic Medical Early Warning Score (PMEWS); to predict ...
Read, R. C., Openshaw, Peter J.M., Semple, Malcolm G., Lim Wei Shen, Semple, MG, Nicholson, K.G., Bannister Barbara, Taylor, B. L., Taylor Bruce L., Puja R. Myles (145227), Read Robert C., Brett, S.J., Semple, M. G., Wei Shen Lim (145243), Semple, M.G., Semple Malcolm G., Karl G. Nicholson (145257), Myles Puja R., Bannister, Barbara, Brett, S. J., Nguyen-Van-Tam, Jonathan S., Stephen J Brett, Jonathan S. Nguyen-Van-Tam (145263), Peter J M Openshaw, Lim, W.S., Taylor, B.L., Myles, P.R., Myles, PR, Barbara Bannister, Jonathan S Nguyen-Van-Tam, James McMenamin (145252), Brett, SJ, Puja R Myles, James McMenamin, Lim, W. S., Brett Stephen J., Nguyen-Van-Tam, JS, Enstone Joanne E., Karl G Nicholson, Wei Shen Lim, Nicholson, Karl G., Enstone, Joanne E., Openshaw Peter J. M., Enstone, J.E., Enstone, J. E., Robert C Read, Stephen J. Brett (145230), Brett, Stephen J., Lim, Wei Shen, McMenamin, J., Bruce L Taylor, Read, Robert C., Read, RC, Peter J. M. Openshaw (145235), McMenamin, J, Myles, Puja R., Joanne E Enstone, Enstone, JE, Nguyen-Van-Tam, J.S., Myles, P. R., Nicholson, KG, Robert C. Read (145234), Read, R.C., Malcolm G Semple, Malcolm G. Semple (80199), Lim, WS, Taylor, BL, Nicholson, K. G., Nguyen-Van-Tam Jonathan S., McMenamin, James, Bruce L. Taylor (145248), Barbara Bannister (145260), Drews, S.J., Nguyen-Van-Tam, J. S., Taylor, Bruce L., Bannister, B., Nicholson Karl G., Openshaw, P. J. M., McMenamin James, Openshaw, PJM, Joanne E. Enstone (145232), Openshaw, P.J.M., Bannister, B   +82 more
core   +1 more source

Beyond Formal Agreements: EU Agencies' Cooperation with Third Countries

JCMS: Journal of Common Market Studies, EarlyView.
ABSTRACT Third countries' participation in European Union (EU) agencies is attracting increasing attention as venues for differentiated European integration. Research has started to vest into the host of formal agreements regulating this cooperation. However, regulatory outreach by EU agencies may be more important than it is stated de jure, as many ...
Thibaud Deruelle, Sandra Lavenex, Matis Poussardin   +2 more
wiley   +1 more source

Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, Australia

Western Pacific Surveillance and Response, 2011
Objective: To describe the demographic and clinical characteristics of patients hospitalized with pandemic A(H1N1) 2009 infection in Queensland, Australia between 25 May and 3 October 2009 and to examine the relationship between timing of antiviral ...
Hai Phung, Frank Beard, Christine Selvey, Ranil Appuhamy, Frances Birrell   +4 more
doaj   +1 more source

Narcolepsy and H1N1 vaccination

Current Opinion in Pulmonary Medicine, 2013
A number of European countries have reported a dramatic increase in the rates of childhood narcolepsy with cataplexy in children immunized with a split-virion adjuvanted swine flu vaccine. Here, we review the strengths and weaknesses of these epidemiological studies and possible neuroimmunological mechanisms.Initial concerns of a 13-fold increased ...
Thebault, Simon, Vincent, Angela, Gringras, Paul   +2 more
openaire   +3 more sources

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, EarlyView.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source