Results 81 to 90 of about 178,155 (246)

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang   +9 more
wiley   +1 more source

Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1. [PDF]

open access: yes, 2011
: Virus outbreaks have been found to be related to the concentration of a new class of genomic peptides, Replikins^1^. The eight genes of H5N1 influenza virus were analyzed for the distribution of Replikin Counts (number Replikins /100 amino acids) in 2 ...
Elenore S. Bogoch, Samuel Bogoch
core   +2 more sources

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

open access: yesVIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang   +5 more
wiley   +1 more source

Bogoch Replikins Pandemic Prevention: Increase of Strain-Specific Influenza Genomic Replikin Counts, Having Predicted Outbreaks and their Location Seven Times Consecutively, Up to Two Years in Advance, Provides Time for Prevention of Pandemics [PDF]

open access: yes, 2012
Earlier studies have shown that the increased concentration of a new class of virus genomic peptides, Replikins, precedes and predicts virus outbreaks. We now find that the area in the genome of the highest concentration of Replikins, and the country in ...
Elenore S. Bogoch, Samuel Bogoch
core   +2 more sources

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

open access: yesVIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu   +10 more
wiley   +1 more source

Immunogenicity and tolerability of an MF59-adjuvanted, egg-derived, A/H1N1 pandemic influenza vaccine in children 6-35 months of age [PDF]

open access: yes, 2014
Background: Vaccines against pandemic A/H1N1 influenza should provide protective immunity in children, because they are at greater risk of disease than adults.
Abarca, Katia   +9 more
core   +2 more sources

Crisis micro‐learning: A framework for understanding the micro‐flow of policy learning and Australia's COVID‐19 response

open access: yesAustralian Journal of Public Administration, EarlyView.
Abstract COVID‐19 has intensified interest in crisis policy learning, yet the micro‐level interactions among political, bureaucratic, and expert actors remain underexplored. We conceptualise an ideal‐type framework for the micro‐flow of crisis learning, an ordinarily epistemic and context‐specific process of individual‐level interactions, where lessons
Neil Mortimer, Nicholas Bromfield
wiley   +1 more source

Influenza A(H1N1) and Pandemic Preparedness Under the Rule of International Law [PDF]

open access: yes, 2009
A novel strain of Influenza A (H1N1) spread rapidly through Mexico in April 2009 and now spans the globe. By the time WHO was notified and responded, geographical containment was not feasible, leading the agency to call for mitigation.
Gostin, Lawrence O.
core   +1 more source

Government support, regional well‐being, and the pivots of UK SMEs during a crisis

open access: yesEuropean Management Review, EarlyView.
Abstract Pivoting—a substantive transformation of the established business model (e.g., reformulation of goods, services, processes, or organizational methods in a new or significantly improved manner)—has emerged as a crisis response strategy of small‐ and medium‐sized enterprises (SMEs).
Chau M. Chu, Bach Nguyen
wiley   +1 more source

Swine influenza virus antibodies in humans, Western Europe, 2009 [PDF]

open access: yes, 2011
Serologic studies for swine influenza viruses (SIVs) in humans with occupational exposure to swine have been reported from the Americas but not from Europe.
Gerloff, Nancy   +8 more
core   +2 more sources

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