Results 51 to 60 of about 44,112 (233)

VIRUS-SPECIFIC HUMORAL IMMUNE RESPONSE ISOTYPIC STRUCTURE IN ADULT PATIENTS HOSPITALIZED WITH INFLUENZA A

Инфекция и иммунитет, 2016
The aim of this investigation was a comparative analysis of isotypic structure of specific antiviral systemic humoral immune response in hospitalized patients with influenza caused by virus A(H3N2) or A(H1N1), including the A(H1N1)pdm09. Paired acute and
V. Z. Krivitskaya, A. A. Vasilieva, E. M. Voytsekhovskaya, E. R. Petrova, M. M. Pisareva, Zh. V. Buzitskaya, E. A. Elpaeva, A. A. Go, L. V. Voloshchuk, N. I. Lvov, T. D. Smirnova, A. A. Sominina   +11 more
doaj   +1 more source

Targeting influenza A virus by splicing inhibitor herboxidiene reveals the importance of subtype-specific signatures around splice sites

Journal of Biomedical Science, 2023
Background The association between M segment splicing and pathogenicity remains ambiguous in human influenza A viruses. In this study, we aimed to investigate M splicing in various human influenza A viruses and characterize its physiological roles by ...
Yi-Ju Han, Kuo-Ming Lee, Guan-Hong Wu, Yu-Nong Gong, Avijit Dutta, Shin-Ru Shih   +5 more
doaj   +1 more source

Respiratory syncytial virus: Clinical and epidemiological pattern in pediatric patients admitted to a children’s hospital between 2000 and 2013 [PDF]

, 2014
INTRODUCTION: Respiratory syncytial virus (RSV) is the major causative organism associated with acute lower respiratory tract infections in children.The objective of this study was to describe the clinical and epidemiological pattern of RSV and identify ...
Bakir, Julia, Castellano, Verónica, Gentile, Ángela, Grobaporto, Marcela, Juárez, María del Valle, Lucion, María Florencia, Mistchenko, Alicia Susana, Romanin, Viviana Sandra, Viegas, Mariana   +8 more
core   +1 more source

Development of DNA-Biochip for Identification of Influenza A Virus Subtypes

Проблемы особо опасных инфекций, 2012
Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase ...
A. N. Shikov, E. I. Sergeeva, O. K. Demina, V. A. Ternovoy, V. V. Ryabinin, E. V. Kostina, E. M. Malkova, A. N. Sinyakov, A. P. Agaphonov   +8 more
doaj   +1 more source

Hemagglutinin sequence conservation guided stem immunogen design from influenza A H3 subtype [PDF]

, 2015
Seasonal epidemics caused by influenza A (H1 and H3 subtypes) and B viruses are a major global health threat. The traditional, trivalent influenza vaccines have limited efficacy because of rapid antigenic evolution of the circulating viruses.
Citron, Michael, Ferrara, Francesca, Flynn, Jessica A, Liang, Xiaoping, Mallajosyula, Vamsee V A, Temperton, Nigel J., Varadarajan, Raghavan   +6 more
core   +4 more sources

Cross-species infectivity of H3N8 influenza virus in an experimental infection in swine [PDF]

, 2015
Avian influenza A viruses have gained increasing attention due to their ability to cross the species barrier and cause severe disease in humans and other mammal species as pigs.
Amadori, Massimo, Baratelli, Massimiliano, Bilato, Dania, Chiapponi, Chiara, Córdoba, Lorena, Del Real, Gustavo, Foni, Emanuela, Fraile Sauce, Lorenzo José, Martín del Burgo, María Ángeles, Martínez, Jorge, Martínez-Orellana, Pamela, Montoya, Maria, Perlin, David S., Razzuoli, Elisabetta, Solórzano, Alicia   +14 more
core   +2 more sources

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow, Calza, Chan, Cosma, De Jong, Farrohi, Ferrara, Fox, Frank, Fulton, Gross, Halloran, Harmon, Hierholzer, Johansson, Johansson, Kendal, Kilbourne, Montomoli, Okuno, O’Neill, Powers, Probert, Rowe, Schild, Schulman, Schulman, Scott, Sylte, Van Assen, Yewdell   +30 more
core   +3 more sources

A Historical Perspective of Influenza A(H1N2) Virus

Emerging Infectious Diseases, 2014
The emergence and transition to pandemic status of the influenza A(H1N1)A(H1N1)pdm09) virus in 2009 illustrated the potential for previously circulating human viruses to re-emerge in humans and cause a pandemic after decades of circulating among animals.
Naomi Komadina, Jodie McVernon, Robert Hall, Karin Leder   +3 more
doaj   +1 more source

A Novel Sequence-Based Antigenic Distance Measure for H1N1, with Application to Vaccine Effectiveness and the Selection of Vaccine Strains [PDF]

, 2011
H1N1 influenza causes substantial seasonal illness and was the subtype of the 2009 influenza pandemic. Precise measures of antigenic distance between the vaccine and circulating virus strains help researchers design influenza vaccines with high vaccine ...
Brown, Caton, Daniels, Deem, Donatelli, Ferguson, K. C. Subieta, K. Pan, KEITEL, Lee, M. W. Deem, Nobusawa, Pan, Rambaut, Smith, Wiley, Zaraket   +16 more
core   +3 more sources

In silico design of cyclic peptides as influenza virus, a subtype H1N1 neuraminidase inhibitor [PDF]

AFRICAN JOURNAL OF BIOTECHNOLOGY, 2012
Nowadays, influenza has become a global public health concern because it is responsible for significant morbidity and mortality due to annual epidemics and unpredictable pandemics. There are only limited options to control this respiratory disease. Vaccine treatment is useless for controlling this disease because of the occurrence of mutation in the ...
Usman Sumo Friend Tambunan, Noval Amri, Arli Aditya Parikesit   +2 more
openaire   +2 more sources