Results 71 to 80 of about 33,674 (168)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, Volume 13, Issue 31, 4 June 2026.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Programmed Cell Death in Chronic Rhinosinusitis

Clinical and Translational Allergy, Volume 16, Issue 6, June 2026.
ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu, Junying Hu, Weigang Gan, Qi Wu, Bing Zhong, Feng Liu   +5 more
wiley   +1 more source

Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells

Respiratory Research, 2005
Background Fatal human respiratory disease associated with influenza A subtype H5N1 has been documented in Hong Kong, and more recently in Vietnam, Thailand and Cambodia. We previously demonstrated that patients with H5N1 disease had unusually high serum
Poon LLM, Long HT, Chan RWY, Chan YO, Nicholls JM, Tsao SW, Chui WH, Cheung CY, Chan MCW, Guan Y, Peiris JSM   +10 more
doaj   +1 more source

Three‐Dimensional Magnetic Multi‐Metallic Nanozymes With Colorimetric and Catalytic Amplification for Rapid and Highly‐Sensitive Detection of Influenza A

Exploration, Volume 6, Issue 3, June 2026.
The application of nanozymes in LFIA greatly improved the situation of insufficient colorimetric signals by catalytic reaction. 3D magnetic multi‐metallic nanozymes integrated the characteristics of great magnetism, enhanced colorimetric signal, and outstanding POD‐like activity, and were applied to LFIA for rapid and accurate detection of Influenza A ...
Zhenzhen Liu, Pengyou Zhou, Xiaofei Jia, Xiaoxian Liu, Yong Yang, Yansong Sun, Rui Xiao   +6 more
wiley   +1 more source

Respiratory Viral Infections in Sickle Cell Anemia: Special Emphasis on H1N1 Co-infection

Oman Medical Journal, 2020
Objectives: Patients with sickle cell anemia (SCA) are immunocompromised and at an increased risk of developing infections. Our aim was to establish the clinical, laboratory, and radiological manifestations of respiratory viral infections in SCA at ...
Salam Alkindi, Taqwa Al-Yahyai, Sameer Raniga, Mohamed Rachid Boulassel, Anil Pathare   +4 more
doaj   +1 more source

Verification of the Combimatrix influenza detection assay for the detection of influenza A subtype during the 2007–2008 influenza season in Toronto, Canada

Virology Journal, 2009
The increase in adamantine resistance in influenza A (H3N2) and the emergence of oseltamivir resistance in influenza A (H1N1) has necessitated the use of rapid methodologies to detect influenza subtype.
Blair Joanne, Eshaghi AliReza, Yeung Rani, Lombos Ernesto, Bolotin Shelly, Drews Steven J   +5 more
doaj   +1 more source

Development and Validation of a Nomogram to Predict Respiratory Failure With Influenza

Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Purpose Influenza‐induced respiratory failure is a severe complication of influenza that can rapidly progress to multi‐organ failure or even death due to severe impairment of pulmonary ventilation or gas exchange function. Early prediction and intervention can decrease the mortality in patients with respiratory failure. Methods A comprehensive
Mingzhen Zhao, Yi Li, Hongxiang Fu, Guanghui Jia, Xing Zhao, Yu Sun, Xingbin Li, Hongbo Zhang, Zhiwei Zhao   +8 more
wiley   +1 more source

[Radioimmunological study of the hemagglutinin of influenza viruses subtype H1N1].

Voprosy virusologii, 1982
Radioimmunoassay were carried out with influenza A/Cambridge/46, A/FM/1/47, A/England/1/51, A/Denwer/1/57, and A/USSR/90/79 of the H1N1 subtype to determine the antigenic determinants of influenza A/USSR/90/77 virus hemagglutinin. The test system included 125I-labeled hemagglutinin of A/USSR/90/77 virus and homologous antiserum to this virus.
A K, Gitel'man, G N, Mukazhanova, I G, Kharitonenkov   +2 more
openaire   +1 more source

CD4+ T-Cell Expansion Predicts Neutralizing Antibody Responses to Monovalent, Inactivated 2009 Pandemic Influenza A(H1N1) Virus Subtype H1N1 Vaccine [PDF]

The Journal of Infectious Diseases, 2012
The ability of influenza vaccines to elicit CD4(+) T cells and the relationship between induction of CD4(+) T cells and vaccine-induced neutralizing antibody responses has been controversial. The emergence of swine-origin 2009 pandemic influenza A virus subtype H1N1 (A[H1N1]pdm09) provided a unique opportunity to examine responses to an influenza ...
Nayak, Jennifer L., Fitzgerald, Theresa F., Richards, Katherine A., Yang, Hongmei, Treanor, John J., Sant, Andrea J.   +5 more
openaire   +2 more sources