Background Swine influenza A virus (IAV-S) is a common cause of respiratory disease in pigs and poses a major public health threat. However, little attention and funding have been given to such studies.
Yuzhong Zhao +10 more
semanticscholar +1 more source
Simultaneous detection and subtyping of H274Y-positive influenza A (H1N1) using pyrosequencing
Introduction: We investigated the frequency of H274Y-positive swine-origin 2009 A (H1N1) influenza virus outbreak in Thailand during May-August 2009. Methodology: This study sought to find Oseltamivir resistance mutation H274Y by using pyrosequencing.
Wasun Chantratita +6 more
openaire +4 more sources
One-way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential [PDF]
We hypothesise that some influenza virus adaptations to poultry may explain why the barrier for human-to-human transmission is not easily overcome once the virus has crossed from wild birds to chickens.
Alexander +101 more
core +2 more sources
Development of DNA-Biochip for Identification of Influenza A Virus Subtypes
Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase ...
A. N. Shikov +8 more
doaj +1 more source
A Novel Sequence-Based Antigenic Distance Measure for H1N1, with Application to Vaccine Effectiveness and the Selection of Vaccine Strains [PDF]
H1N1 influenza causes substantial seasonal illness and was the subtype of the 2009 influenza pandemic. Precise measures of antigenic distance between the vaccine and circulating virus strains help researchers design influenza vaccines with high vaccine ...
Brown +16 more
core +3 more sources
Comparison of Patients Hospitalized With Influenza A Subtypes H7N9, H5N1, and 2009 Pandemic H1N1 [PDF]
Les virus de la grippe A(H7N9) isolés chez l'homme présentent des caractéristiques suggérant une adaptation partielle aux mammifères. Pour fournir des informations sur la pathogenèse de l'infection par le virus H7N9, nous avons comparé les facteurs de risque, la présentation clinique et la progression des patients hospitalisés pour des infections par ...
Chen Wang +29 more
openaire +5 more sources
Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow +30 more
core +3 more sources
In silico modification of oseltamivir as neuraminidase inhibitor of influenza A virus subtype H1N1 [PDF]
This research focused on the modification of the functional groups of oseltamivir as neuraminidase inhibitor against influenza A virus subtype H1N1. Interactions of three of the best ligands were evaluated in the hydrated state using molecular dynamics simulation at two different temperatures. The docking result showed that AD3BF2D ligand (N-[(1S,6R)-5-
Tambunan, Usman Sumo Friend +2 more
openaire +2 more sources
A Historical Perspective of Influenza A(H1N2) Virus
The emergence and transition to pandemic status of the influenza A(H1N1)A(H1N1)pdm09) virus in 2009 illustrated the potential for previously circulating human viruses to re-emerge in humans and cause a pandemic after decades of circulating among animals.
Naomi Komadina +3 more
doaj +1 more source
Genetic and biological characterisation of an avian-like H1N2 swine influenza virus generated by reassortment of circulating avian-like H1N1 and H3N2 subtypes in Denmark [PDF]
BACKGROUND: The influenza A virus subtypes H1N1, H1N2 and H3N2 are the most prevalent subtypes in swine. In 2003, a reassorted H1N2 swine influenza virus (SIV) subtype appeared and became prevalent in Denmark.
Bragstad, Karoline +8 more
core +1 more source

