A reassortant H9N2 influenza virus containing 2009 pandemic H1N1 internal-protein genes acquired enhanced pig-to-pig transmission after serial passages in swine [PDF]
Avian H9N2 and 2009 pandemic H1N1 (pH1N1) influenza viruses can infect pigs and humans, raising the concern that H9N2: pH1N1 reassortant viruses could emerge.
Ma, Wenjun +5 more
core +2 more sources
Possible computational filter to detect proteins associated to influenza A subtype H1N1.
The design of drugs with bioinformatics methods to identify proteins and peptides with a specific toxic action is increasingly recurrent. Here, we identify toxic proteins towards the influenza A virus subtype H1N1 located at the UniProt database. Our quantitative structure-activity relationship (QSAR) approach is based on the analysis of the linear ...
Thomas Buhse +3 more
openaire +4 more sources
Electrochemical Breath Sensors in Medical Diagnostics: Emerging Trends and Future Directions
Electrochemical breath sensors (EBSs) are emerging as powerful tools for noninvasive health diagnostics. This perspective highlights recent advances in EBS technologies, explores their potential in mental health monitoring via gut‐derived volatile organic compounds, and outlines future directions for achieving sensitive, selective, and clinically ...
Natalie E. Strom +2 more
wiley +1 more source
Isolation and Characterization of H1 Subtype Swine Influenza Viruses Recently Circulating in China
Pigs serve as a mixing vessel for influenza viruses and can independently promote the emergence of pandemic strains in humans. During our surveillance of pig populations from 2021 to 2023 in China, 11 H1 subtype swine influenza viruses (SIVs) were ...
Minghao Yan +12 more
doaj +1 more source
Molecular detection of H1N1 virus by conventional reverse transcription PCR coupled with nested PCR
Influenza A pdm09 virus has been spreading worldwide and creates a serious public health threat. Among different subtypes/lineages of swine influenza A viruses, the H1N1 subtype is more prevalent in all-over world infections followed by H3N2 which is ...
Ravina +5 more
doaj +1 more source
Bee products as alternatives in the treatment of viral infections
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
Mouse Models of Influenza Infection with Circulating Strains to Test Seasonal Vaccine Efficacy
Influenza virus infection is a significant cause of morbidity and mortality worldwide. The surface antigens of influenza virus change over time blunting both naturally acquired and vaccine induced adaptive immune protection.
Helen T. Groves +11 more
doaj +1 more source
Identification of a highly conserved H1 subtype-specific epitope with diagnostic potential in the hemagglutinin protein of influenza A virus. [PDF]
Subtype specificity of influenza A virus (IAV) is determined by its two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA). For HA, 16 distinct subtypes (H1-H16) exist, while nine exist for NA.
Rongmao Zhao +8 more
doaj +1 more source
Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
wiley +1 more source
Generation of a Reassortant Influenza A Subtype H3N2 Virus Expressing Gaussia Luciferase
Reporter influenza A viruses (IAVs) carrying fluorescent or luminescent genes provide a powerful tool for both basic and translational research. Most reporter IAVs are based on the backbone of either subtype H1N1 viruses, A/Puerto Rico/8/1934 (PR8) or A ...
Lin Wang +6 more
doaj +1 more source

