Results 41 to 50 of about 63,963 (192)

A monoclonal antibody targeting the C-terminal of α-synuclein fibrils mitigates pathology in a Parkinson’s disease model

Cell Reports
Summary: Parkinson’s disease (PD) pathogenesis is driven by α-synuclein (α-syn) amyloid aggregation, with the flexible C-terminal region mediating pathological interactions with cellular receptors and facilitating disease propagation and ...
Shuyi Zeng, Shengnan Zhang, Xun Gui, Danni Li, Shiran Lv, Hui Dong, Qianhui Xu, Jian Wu, Hongyuan Ren, Qinyue Zhao, Houfang Long, Yifan Yu, Shouqiao Hou, Weidong Le, Mengqi Fan, Datao Liu, Dan Li, Cong Liu   +17 more
doaj   +1 more source

Contribution of FliC to Epithelial Cell Invasion by Enterohemorrhagic Escherichia coli O113:H21 [PDF]

Infection and Immunity, 2006
ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) O113:H21 can invade epithelial cells. In this study, we found that invasion but not adherence was inhibited by anti-FliC H21 specific antibodies. In addition, deletion of fliC H21
Shelley N, Luck, Luminita, Badea, Vicki, Bennett-Wood, Roy, Robins-Browne, Elizabeth L, Hartland   +4 more
openaire   +2 more sources

Editorial: Aerospace health and safety: today and the future, volume II [PDF]

Frontiers in Public Health
Mardi Crane-Godreau, Eileen McNeely, Philip Parks, Russell Tontz, Christopher Scheibler   +4 more
doaj   +2 more sources

Approximate Sum-Capacity of the Y-channel

, 2013
A network where three users want to establish multiple unicasts between each other via a relay is considered. This network is called the Y-channel and resembles an elemental ingredient of future wireless networks.
Avestimehr, A. Salman, Chaaban, Anas, Sezgin, Aydin   +2 more
core   +1 more source

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

Advanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee, Yuen Ting Lam, Alex H. P. Chan, Praveesuda L. Michael, Timothy C. Mitchell, Jui Chien Hung, Miguel Santos, Khoon S. Lim, Richard P. Tan, Steven G. Wise   +9 more
wiley   +1 more source

Tax policy reform and universal basic income effectiveness in a currency union: Implications for long-term growth, inequality, and welfare

Journal of Government and Economics, 2023
This paper aims to assess tax policy reforms that can sustain universal basic income programs and foster long-term growth and welfare in a currency union that faces fiscal rule constraints and inequality. To address this ongoing government and economics’
Thierry U. KAME BABILLA
doaj   +1 more source

Virulence profile comparison between LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated from cattle and humans [PDF]

, 2010
For comparison purposes, the prevalence of 8 virulence markers was investigated, by PCR, in 153 cattle and 47 human Locus for Enterocyte Effacement (LEE)-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated in Argentina.
Galli, Lucía, Irino, Kinue, Leotta, Gerardo Anibal, Miliwebsky, Elizabeth, Rivas, Marta   +4 more
core   +1 more source

Fluorescence Properties and Mg2+ Selectivity of Aryl‐Alkynyl Derivatives of the o‐Aminophenoltriacetate (APTRA) Ligand

Chemistry – A European Journal, EarlyView.
It is a challenge to improve the selectivity of high‐denticity ligands for Mg2+ over Ca2+. We show that in aryl‐alkynyl derivatives of APTRA, electron‐withdrawing substituents lower the binding affinity for Ca2+ more than Mg2+, making the ligand more selective for Mg2+.
Laura L. Duncan, Christopher Hogg, J. A. Gareth Williams   +2 more
wiley   +1 more source

Liquidity Constraints and Tax Liability Targeting of Banks in Ghana: Analysis of Persistence and Distance to Target

Foundations of Management
This paper examines the effect of liquidity constraints on tax liability targeting among banks in Ghana, with emphasis on the persistence and speed of adjustment toward tax targets.
BOATENG Kwakye, OMANE-ANTWI Kwame Bosiako, QUEKU Yaw Ndori   +2 more
doaj   +1 more source

Hardy-Sobolev Equations on Compact Riemannian Manifolds

, 2014
Let (M,g) be a compact Riemannien Manifold of dimension n > 2, x_0 in M a fix and singular point and s in (0,2). We let 2*(s) = 2(n-s)/(n-2) be the critical Hardy-Sobolev exponent.
Jaber, Hassan
core   +1 more source