Results 61 to 70 of about 17,190 (226)

ESCIN MITIGATES HYPOXIA MIMICKING NCI-H23 CELLS THROUGH MODULATION OF MMPs, HIF-1α AND HIF-2α

open access: yes, 2020
Objective: The objective of the study is to investigate the effect of escin in hypoxia mimicked NCI-H23 cells through the modulation of matrix metalloproteinases (MMPs) 2 and 9.
SUDHANDIRAN, GANAPASAM   +1 more
core  

MLH1-deficient NCI-H23 subclones exhibit increased resistance to chemotherapeutic drugs.

open access: yes, 2013
NCI-H23 subclones that were uninduced or induced for MLH1 shRNA were treated with etoposide (A-C) or temozolomide (D-F). (A, D) Cells were treated with compound at the concentrations indicated, and cell viability was assessed at 4d using a Cell Titer-Glo
Julie M. Bailis (477608)   +5 more
core   +1 more source

Untersuchungen zu Regulationsmechanismen von Hypoxie-induzierbaren-Faktoren und deren Zielgenen in den Tumorzelllinien H23, A549 und H69

open access: yes, 2009
Die Karzinogenese ist ein multi-komplexer Prozess, der durch DNA-Schädigung bzw. Mutation, Überexpression von Onkogenen und / oder Funktionsverlust von Tumorsuppressorgenen zu einer dysregulierten Zellproliferation führt.
Mahlik, Pierre Pasqual   +1 more
core   +2 more sources

Advising on Antidepressant Use in Pregnancy: Are We All on the Same Page?

open access: yesAsia-Pacific Psychiatry, Volume 18, Issue 3, September 2026.
ABSTRACT Purpose Perinatal mood disorders are associated with adverse maternal and neonatal outcomes and affect 15%–20% of pregnant people. Guidelines recommend SSRIs when non‐pharmacological therapies are ineffective, yet antenatal depression remains undertreated.
Lucy Charlotte Broughton   +3 more
wiley   +1 more source

RRM1 interacts with RNF2 and Bmi1.

open access: yes, 2014
A) Endogenous interaction between RRM1 and RNF2 in H23-WT. Cell lysate was subjected to IP using control IgG Ab (lane 2) or anti-RRM1 Ab (lane 3), followed by immunoblotting (IB) with the indicated antibodies. Expression of RNF2 and RRM1 in cell lysates (
Xin Li (51274)   +3 more
core   +1 more source

Barriers to the Accessibility of Childcare Services for Children With Disabilities Aged 0 to 5 Years: Perspectives of Parents and Childcare Staff

open access: yesChildren &Society, Volume 40, Issue 4, Page 823-835, July 2026.
ABSTRACT According to Article 23 of the United Nations Convention on the Rights of the Child, children with disabilities are entitled to education, including access to high‐quality childcare services. Despite international and national commitments to inclusion, persistent obstacles continue to limit equitable access to childcare services for children ...
François Routhier   +23 more
wiley   +1 more source

Induction of MLH1 shRNA decreases MLH1 protein levels.

open access: yes, 2013
MLH1 protein levels in NCI-H23 subclones induced for the MLH1 928 shRNA were compared to MLH1 protein levels in the NCI-H23 parental cells (H23). Protein lysates were analyzed by SDS-PAGE and immunoblotting for the MLH1 and MSH2 protein levels. GAPDH was
Julie M. Bailis (477608)   +5 more
core   +1 more source

Stage‐Specific Indicators of Northern Yellowtail Rockfish (Sebastes flavidus) Recruitment in the California Current Ecosystem

open access: yesFisheries Oceanography, Volume 35, Issue 4, Page 630-649, July 2026.
ABSTRACT Oceanographic and ecological conditions can be used to inform forecasts and decision‐making for marine resources, but the dominant drivers of recruitment variability remain poorly understood for many fish stocks. We developed a conceptual life‐history model of the oceanographic and ecological variables that influence the recruitment of ...
Megan L. Feddern   +3 more
wiley   +1 more source

Evolution of Crematogaster sordidula (Hymenoptera, Formicidae) Ants in the Mediterranean Region During Plio‐Pleistocene Climatic Changes

open access: yesZoologica Scripta, Volume 55, Issue 4, Page 615-638, July 2026.
ABSTRACT Understanding insect responses to global climate change involves identifying strategies used during past climate oscillations. Phylogeography offers a powerful framework to unravel how historical climatic and geological events have shaped the spatial genetic patterns of species, providing critical insights into evolutionary processes, whereas ...
Jody H. Voges   +12 more
wiley   +1 more source

Allocating Income from Targeting Subsidy to the Production Sectors: Distributional Impacts of Different Alternatives for the Iranian Households [PDF]

open access: yesپژوهشهای اقتصادی, 2014
This study investigates alternative options for allocating incomes from targeting subsidy program to different production sectors and its consequences on income distribution among Iranian households.
Vahideh Ansari, Habibollah Salami
doaj  

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