Results 71 to 80 of about 47,678 (217)

Artemisia santolinifolia-Mediated Chemosensitization via Activation of Distinct Cell Death Modes and Suppression of STAT3/Survivin-Signaling Pathways in NSCLC

open access: yesMolecules, 2021
Conventional chemotherapy remains an integral part of lung cancer therapy, regardless of its toxicity and drug resistance. Consequently, the discovery of an alternative to conventional chemotherapy is critical.
Uyanga Batbold, Jun-Jen Liu
doaj   +1 more source

Extremal Multicenter Black Holes: Nilpotent Orbits and Tits Satake Universality Classes

open access: yes, 2012
Four dimensional supergravity theories whose scalar manifold is a symmetric coset manifold U[D=4]/Hc are arranged into a finite list of Tits Satake universality classes. Stationary solutions of these theories, spherically symmetric or not, are identified
A Ceresole   +99 more
core   +1 more source

Barriers to the Accessibility of Childcare Services for Children With Disabilities Aged 0 to 5 Years: Perspectives of Parents and Childcare Staff

open access: yesChildren &Society, EarlyView.
ABSTRACT According to Article 23 of the United Nations Convention on the Rights of the Child, children with disabilities are entitled to education, including access to high‐quality childcare services. Despite international and national commitments to inclusion, persistent obstacles continue to limit equitable access to childcare services for children ...
François Routhier   +23 more
wiley   +1 more source

On the conflict between science and ethics: the case of the moggel, Labeo umbratus (Teleostei: Cyprinidae) from South Africa

open access: yesJournal of Fish Biology, EarlyView.
Abstract Recent molecular evidence showed that Labeo umbratus comprises two allopatrically distributed genetic lineages, a northern lineage confined to the Orange‐Vaal River system where this species was originally described and a southern lineage with three geographically separated haplogroups (western, central and eastern) distributed across multiple
Mpho Ramoejane   +3 more
wiley   +1 more source

Capacidad redistributiva de los gastos fiscales en el contexto de la polarización del ingreso en México, 2008-2012

open access: yesEconomía Teoría y Práctica, 2016
El presente trabajo busca abordar el concepto de gasto fiscal a partir del caso del impuesto negativo por enajenación de gasolinas y diesel en México para destacar su potencial redistributivo y analizar el comportamiento territorial de los niveles de ...
José Luis Manzanares Rivera
doaj  

Cerebral oxygen extraction across different exercise intensities: Role of arterial PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$

open access: yesExperimental Physiology, EarlyView.
Abstract Stability in cerebral oxygen extraction fraction (OEF) is typically determined by alterations in cerebral blood flow (CBF). At rest, arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$) and OEF exhibit a strong inverse relationship owing to the powerful influence of PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$
L. Madden Brewster   +11 more
wiley   +1 more source

MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good?

open access: yesBMC Cancer, 2018
Background Targeted therapies are based on exploiting cancer-cell-specific genetic features or phenotypic traits to selectively kill cancer cells while leaving normal cells unaffected. Oxidative stress is a cancer hallmark phenotype.
Hussein H. K. Abbas   +4 more
doaj   +1 more source

Elevated carotid body tonic activity contributes to ventilatory acclimatization and de‐acclimatization to high altitude at rest and during exercise

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Participants spent 13 days at high altitude (3800 m), where the reduced inspired oxygen pressure (↓PiO2$ \downarrow {P_{{\mathrm{i}}{{\mathrm{O}}_2}}}$) which elicited ventilatory acclimatization and increased inhibition of ventilation by transient hyperoxia (ΔV̇E$\Delta {\dot V_{\mathrm{E}}}$).
Ayechew A. Getu   +6 more
wiley   +1 more source

Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Objective To investigate the lung cancer-promoting mechanism of mesenchymal stem cell-secreted extracellular vesicles (MSC-EV). Methods EV were isolated from culture media of human bone marrow-derived MSCs that were pre-challenged with or without hypoxia
Weihua Ren   +7 more
doaj   +1 more source

Parenting Experiences Among Adults With Intellectual Disabilities: A Scoping Review

open access: yesBritish Journal of Learning Disabilities, Volume 54, Issue 1, Page 15-27, March 2026.
ABSTRACT Background Parents with intellectual disabilities face many barriers to accessing efficacious supports and services designed to support thriving in their parenting role. A review of research in this area may identify a nuanced understanding of common experiences, including potential barriers and facilitators to success and thriving.
Rae Morris   +4 more
wiley   +1 more source

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