H3.1 Eviction Marks Female Germline Precursors in Arabidopsis [PDF]
Plants, 2020 In flowering plants, germline precursors are differentiated from somatic cells. The female germline precursor of Arabidopsis thaliana is located in the internal (nucellar) tissue of the ovule, and is known as the Megaspore Mother Cell (MMC).
Elvira Hernandez-Lagana, Daphné Autran
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Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements [PDF]
iScience, 2020 Summary: Replication-dependent canonical histone messenger RNAs (mRNAs) do not terminate with a poly(A) tail at the 3′ end. We previously demonstrated that exposure to arsenic, an environmental carcinogen, induces polyadenylation of canonical histone H3 ...
Danqi Chen +15 more
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The plant-specific histone residue Phe41 is important for genome-wide H3.1 distribution [PDF]
Nature Communications, 2018 The canonical histone variant H3.1 of vascular plants contains a conserved Phe residue at position 41 that is unique to the plant kingdom. Here, Lu et al.
Li Lu +3 more
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Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones
eLife, 2020 Lysine 27-to-methionine (K27M) mutations in the H3.1 or H3.3 histone genes are characteristic of pediatric diffuse midline gliomas (DMGs). These oncohistone mutations dominantly inhibit histone H3K27 trimethylation and silencing, but it is unknown how ...
Jay F Sarthy +10 more
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Genome-wide analysis of histone H3.1 and H3.3 variants in Arabidopsis thaliana [PDF]
Proceedings of the National Academy of Sciences, 2015 Nucleosomes package eukaryotic DNA and are composed of four different histone proteins, designated H3, H4, H2A, and H2B. Histone H3 has two main variants, H3.1 and H3.3, which show different genomic localization patterns in animals.Weprofiled H3.1 and H3.
Desvoyes, Bénédicte +5 more
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Random coil to globular thermal response of a protein (H3.1) with three knowledge-based coarse-grained potentials. [PDF]
PLoS ONE, 2012 The effect of temperature on the conformation of a histone (H3.1) is studied by a coarse-grained Monte Carlo simulation based on three knowledge-based contact potentials (MJ, BT, BFKV).
Ras B Pandey, Barry L Farmer
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Plasma H3.1 nucleosomes as biomarkers of infection, inflammation and organ failure. [PDF]
Crit CareNeutrophil extracellular traps (NETs) are a vital part of the innate immune response, while excessive NET formation can cause tissue damage. H3.1 nucleosomes, a component of NETs, have emerged as a potential biomarker. This study aimed to evaluate H3.1 nucleosomes in critical illness, assessing their relationship with sepsis, organ failure ...
Filippini DFL +8 more
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Dynamic Activity of Histone H3-Specific Chaperone Complexes in Oncogenesis
Frontiers in Oncology, 2022 Canonical histone H3.1 and variant H3.3 deposit at different sites of the chromatin via distinct histone chaperones. Histone H3.1 relies on chaperone CAF-1 to mediate replication-dependent nucleosome assembly during S-phase, while H3.3 variant is ...
Ting Wen, Qiao Yi Chen
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The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication [PDF]
Science, 2022 The tail of replication-dependent histone H3.1 varies from that of replication-independent H3.3 at the amino acid located at position 31 in plants and animals, but no function has been assigned to this residue to demonstrate a unique and conserved role for H3.1 during replication.
Hossein Davarinejad +18 more
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The differential mobilization of histones H3.1 and H3.3 by herpes simplex virus 1 relates histone dynamics to the assembly of viral chromatin. [PDF]
PLoS Pathogens, 2013 During lytic infections, HSV-1 genomes are assembled into unstable nucleosomes. The histones required for HSV-1 chromatin assembly, however, are in the cellular chromatin. We have shown that linker (H1) and core (H2B and H4) histones are mobilized during
Kristen L Conn +2 more
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